Last update 21 Nov 2024

Sonlicromanol

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(S)-6-hydroxy-2,5,7,8-tetramethyl-N-((R)-piperidin-3-yl)chroman-2-carboxamide hydrochloride
Target
Mechanism
PGES inhibitors(Prostaglandin E synthase inhibitors)
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 3
First Approval Date-
RegulationRare Pediatric Disease (US), Orphan Drug (EU)
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Structure

Molecular FormulaC19H28N2O3
InChIKeyLZYWLEPSQNXESC-KUHUBIRLSA-N
CAS Registry1541170-75-5

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
MELAS SyndromePhase 3-02 Jan 2025
Noninsulin-Dependent Diabetes Mellitus With DeafnessPhase 3-02 Jan 2025
Ophthalmoplegia, Chronic Progressive ExternalPhase 2
DE
09 Aug 2021
Ophthalmoplegia, Chronic Progressive ExternalPhase 2
GB
09 Aug 2021
Ophthalmoplegia, Chronic Progressive ExternalPhase 2
DK
09 Aug 2021
Ophthalmoplegia, Chronic Progressive ExternalPhase 2
NL
09 Aug 2021
Leigh DiseasePhase 2
NL
01 Feb 2021
Optic Atrophy, Hereditary, LeberPhase 1
BE
01 May 2015
Mitochondrial DiseasesIND Approval
US
14 Nov 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
27
lhdptayuka(vlvxuopsnu) = hvyskfzaqs ajlrencxfm (hlrrqfrfqg )
Negative
22 Nov 2022
Placebo
-
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Clinical Trial

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Approval

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Regulation

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