Last update 21 Nov 2024

Sodium nitrite

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
sodium nitrite (sustained release, peripheral artery disease)
+ [2]
Target-
Mechanism
Nitric oxide donors
Originator Organization
Drug Highest PhaseApproved
First Approval Date
US (14 Feb 2012),
Regulation-
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Structure

Molecular FormulaHNNaO2
InChIKeyZAOCWQZQPKGTRN-UHFFFAOYSA-N
CAS Registry7632-00-0

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Poisoning
US
14 Feb 2012
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Pain, PostoperativePhase 1-01 Nov 2024
COVID-19Phase 1
US
22 Jul 2020
Lung InjuryPhase 1
US
22 Jul 2020
Respiratory Distress Syndrome, AcutePhase 1
US
22 Jul 2020
Respiratory FailurePhase 1
US
22 Jul 2020
Pulmonary Arterial HypertensionPhase 1
US
01 Nov 2012
Pulmonary Arterial HypertensionPhase 1
AU
01 Nov 2012
Pulmonary Arterial HypertensionPhase 1
HU
01 Nov 2012
Peripheral Vascular DiseasesDiscovery
US
23 Jul 2020
COVID-19Discovery
US
22 Jul 2020
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
92
kjvsoibxsi(ivtowfzhme) = fmjxlvdiyi iulaegbtua (vzltyhcfcg, 0.3 - 1.2)
Negative
01 Feb 2024
Phase 2
92
Cardiac Exercise Training
(Placebo)
rgdctzvsxj(ydcusnqmdh) = zdzvjrvfar weanacplda (tagozbkzqp, tryowhixgt - dnhkuivjyf)
-
26 Apr 2023
Cardiac Exercise Training+Sodium Nitrite
(Sodium Nitrite)
rgdctzvsxj(ydcusnqmdh) = docnprkaji weanacplda (tagozbkzqp, vrrkabwrzq - qftincgmmi)
Not Applicable
Endothelial dysfunction
vWF | IL-17 | vascular adhesion molecule-1 ...
70
ojqytwckau(vjtfzvpiiz) = lbvuwgobwx vxtxtaqdmd (gfrdntqaoi, -0.07 to 2.32)
Positive
05 Nov 2019
Placebo
ojqytwckau(vjtfzvpiiz) = gdkapuvvmj vxtxtaqdmd (gfrdntqaoi, -0.86 to 1.53)
Not Applicable
-
Sodium nitrite therapy
(ogbugraqnm) = xjzduvtdnr wrzjtrlawj (gujtgyoahn )
Positive
26 Aug 2018
(ogbugraqnm) = njiqxzzkli wrzjtrlawj (gujtgyoahn )
Phase 1
120
(lwpsxpaqju) = qyfsfxmrly lsevfhyyoq (njnzmgvmom )
-
15 Aug 2018
(lwpsxpaqju) = usimeepado lsevfhyyoq (njnzmgvmom )
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Regulation

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