Last update 21 Jun 2024

Foralumab

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
NI-0401, NI-0401/α-CD3, TZLS-401
Target
Mechanism
CD3ε inhibitors(CD3e molecule inhibitors)
Originator Organization
Inactive Organization
Drug Highest PhasePhase 2
First Approval Date-
Regulation-

External Link

KEGGWikiATCDrug Bank
-Foralumab-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Multiple Sclerosis, Secondary ProgressivePhase 2
US
15 Nov 2023
Multiple SclerosisPhase 2
GB
27 Apr 2023
COVID-19Phase 2-30 Apr 2022
COVID-19 respiratory infectionPhase 2-30 Apr 2022
Diabetes Mellitus, Type 2Phase 2-01 Dec 2017
Nonalcoholic SteatohepatitisPhase 2-01 Dec 2017
Acute cellular graft rejectionPhase 2
FR
01 Aug 2007
Acute rejection of renal transplantPhase 2
FR
01 Aug 2007
Crohn DiseasePhase 2
NL
13 Jun 2006
Diabetes Mellitus, Type 1Phase 2
EU
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
6
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Positive
25 Apr 2024
Phase 2
10
eohywidyqu(pqwmsahoej) = six out of eight Intermediate Size Patient Population Expanded Access (EA) patients have shown improvements in fatigue scores. PET scan findings showing a reduction in microglial activation was also seen in the six patients with MFIS score improvement at the three-month evaluation period. pparickhjq (jfthnxukmh )
Positive
08 Jan 2024
Phase 1
2
rgduffkmzg(pcrzfaujcd) = The patient showed clinically significant improvement on the Extended Disability Status Scale (EDSS) aemzlqyube (ljaghcdaib )
Positive
20 Sep 2022
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Core Patent

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Clinical Trial

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Approval

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Regulation

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