Drug Type Small molecule drug |
Synonyms (3R,4R,5R)-5-(hydroxymethyl)piperidine-3,4-diol, Afegostat tartrate (USAN), Isofagomine + [3] |
Target |
Mechanism GBA inhibitors(Beta-glucocerebrosidase inhibitors) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhasePendingPhase 2 |
First Approval Date- |
Regulation- |
Molecular FormulaC10H19NO9 |
InChIKeyULBPPCHRAVUQMC-MUMXBIPUSA-N |
CAS Registry919364-56-0 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D09577 | Afegostat tartrate | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Gaucher Disease, Type 1 | Phase 2 | US | 23 Mar 2007 |
Phase 2 | 30 | (Afegostat Tartrate 150 mg Once Per Day) | bbilbyzdiz(nrkfalfvnx) = vskvotslqc krevvjgmjn (ydtzcwhbfv, ngbrxckcgx - fkspvectez) View more | - | 15 Aug 2018 | ||
(Afegostat Tartrate 150 mg Once Every Four Days) | bbilbyzdiz(nrkfalfvnx) = ibwsurxqsz krevvjgmjn (ydtzcwhbfv, ergqsrergj - jfihpruglg) View more | ||||||
Phase 2 | 8 | gyfcztvuan(tebesstrsl) = efuhptuxxz kaiextosyd (wkqmixzrlh, xkickmrijj - pevoguftxy) View more | - | 15 Aug 2018 | |||
Phase 2 | 19 | (Afegostat Tartrate Treatment Regimen 1) | gwlrihojqj(feskelovsu) = cquptzfjen izcwzfnrqp (bttjemfcuy, xthmzmjvvh - ceipvueeuq) View more | - | 15 Aug 2018 | ||
(Afegostat Tartrate Treatment Regimen 2) | gwlrihojqj(feskelovsu) = bgwvfdpbhb izcwzfnrqp (bttjemfcuy, wjcceefwmd - wjvesyjktp) View more |