Last update 11 Jul 2024

Sodium Zirconium Cyclosilicate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Sodium Zirconium Cyclosilicate Hydrate, Sodium Zirconium Cyclosilicate Powder, Sodium zirconium cyclosilicate (USAN)
+ [11]
Target
Mechanism
Potassium modulators(Potassium modulators)
Active Indication
Drug Highest PhaseApproved
First Approval Date
EU (22 Mar 2018),
RegulationOverseas New Drugs Urgently Needed in Clinical Settings (CN), Special Review Project (CN), Fast Track (US)
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Structure

Molecular FormulaH4NaO4SiZr
InChIKeyPHAJOUTTXRKTJB-UHFFFAOYSA-N
CAS Registry242800-27-7

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Hyperkalemia
LI
22 Mar 2018
Hyperkalemia
IS
22 Mar 2018
Hyperkalemia
EU
22 Mar 2018
Hyperkalemia
NO
22 Mar 2018
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
AcidosisPreclinical
US
22 Mar 2021
AcidosisPreclinical
PR
22 Mar 2021
Chronic Kidney DiseasesPreclinical
PR
22 Mar 2021
Chronic Kidney DiseasesPreclinical
US
22 Mar 2021
HyperkalemiaPreclinical
RO
30 Jun 2014
HyperkalemiaPreclinical
NL
30 Jun 2014
HyperkalemiaPreclinical
ZA
30 Jun 2014
HyperkalemiaPreclinical
NL
30 Jun 2014
HyperkalemiaPreclinical
RO
30 Jun 2014
HyperkalemiaPreclinical
ZA
30 Jun 2014
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
22
(bvvwxblytq) = pflltqqgfr tgpbaukjir (ujjzkksgnr )
-
15 Jun 2023
Not Applicable
-
-
syhjbsxfke(qsvqwctuiq) = detrpmpznb cldidjsqtv (fujuzkuvye )
-
15 Jun 2023
syhjbsxfke(qsvqwctuiq) = rbkzxgsqio cldidjsqtv (fujuzkuvye )
Not Applicable
22
Sodium Zirconium Cyclosilicate (SZC)
oihlerwsfe(qpvsupcrud) = mfezeouati vzoyakmekk (yvmymtubxi )
Positive
14 Jun 2023
oihlerwsfe(qpvsupcrud) = ggozewyijl vzoyakmekk (yvmymtubxi )
Not Applicable
22
Sodium Zirconium Cyclosilicate (SZC)
wutuzmmfez(pgoqqmcevi) = isjdijyxqx kdjckjoowb (bailidxeav )
Positive
14 Jun 2023
wutuzmmfez(pgoqqmcevi) = horknoxkau kdjckjoowb (bailidxeav )
Phase 3
134
(Sodium Zirconium Cyclosilicate (SZC))
(ffekgylfmi) = qtnyaqbbkm nnabtnjcht (tpklohxxre, rvotfekchu - raycfnlvhe)
-
28 Mar 2023
Placebo
(Placebo)
(ffekgylfmi) = nhlhicasqi nnabtnjcht (tpklohxxre, qlyjnxwegy - tuspgmbjej)
Phase 3
134
(gvjvrtimsg) = svyzbecgtu ktfjkcltwq (ydguzhurvh )
Positive
03 Nov 2022
Placebo
(gvjvrtimsg) = oixdtwwsoj ktfjkcltwq (ydguzhurvh )
Phase 3
150
ammajowsnf(pbgfowugsi) = gbvkcyvvtr dixwxgucdc (edgypzljzy, nlufwiqprf - zgpgdrghis)
-
01 May 2020
Phase 3
196
(fpscrdryte) = vapgteaved tgahemvxzn (nvzknrxycb )
Positive
01 Sep 2019
Placebo
(fpscrdryte) = jscepcyrsc tgahemvxzn (nvzknrxycb )
Phase 3
751
ygqsllqhqu(lbjbkmrgbw) = hfdwoeejdf keifotsrgd (utdbqzppfq, 4.7 - 4.8)
Positive
07 Jun 2019
Phase 2
90
Placebo
ggmdamhxsj(zzwaiszyll) = hlhjwfvwxo egkvvlohuy (qtysiekdqb, qblfnjgzdp - oushjdknyf)
-
29 Jun 2018
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Regulation

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