Drug Type Small molecule drug |
Synonyms Diquafosol, Diquafosol sodium (JAN), Diquafosol Tetrasodium + [19] |
Target |
Mechanism P2Y2 receptor agonists(Purinergic receptor P2Y2 agonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date JP (16 Apr 2010), |
Regulation- |
Molecular FormulaC18H26N4Na4O23P4 |
InChIKeyMHPMESDJCUICEY-FNXFGIETSA-N |
CAS Registry211427-08-6 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D03864 | Diquafosol Sodium |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Dry Eye Syndromes | KR | 30 Dec 2011 | |
Xerophthalmia | JP | 16 Apr 2010 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Kerato conjunctivitis sicca | Phase 3 | - | 01 Apr 2002 | |
Cataract | Phase 2 | ID | 02 Oct 2022 | |
Bronchitis | Phase 2 | US | - | - |
Corneal Ulcer | Phase 2 | US | - | - |
Cystic Fibrosis | Phase 1 | US | - | - |
Cystic Fibrosis | Phase 1 | GB | - | - |
Pulmonary Disease, Chronic Obstructive | Phase 1 | US | - | - |
Pulmonary Disease, Chronic Obstructive | Phase 1 | GB | - | - |
Not Applicable | Matrix metalloproteinase-9 (MMP-9) | - | kelxbgchqp(azfupbdfwo) = dakgyxdtxu kenowpkgeb (frbpuouazc ) View more | Positive | 13 Dec 2023 | ||
Not Applicable | - | sipgemtqmm(mxummiweic) = zmckbydzck lqfpwlephe (cdqbecxchj ) | - | 03 Jul 2023 | |||
Not Applicable | 30 | gpupkenhuz(xsutfxdaqh) = bpgnmxuglo mjtbvrsvnl (clzwgvdhap ) View more | Positive | 19 Jan 2022 | |||
Hyaluronate | gpupkenhuz(xsutfxdaqh) = rbimlyajat mjtbvrsvnl (clzwgvdhap ) View more | ||||||
Not Applicable | - | llmnljdfbi(cypahqzsub) = ztahzsgjlp wiuabiywnh (ddocdovozt ) | - | 01 Jul 2018 | |||
Artificial tears | llmnljdfbi(cypahqzsub) = lrbeajfbmj wiuabiywnh (ddocdovozt ) | ||||||
Not Applicable | - | ieihlpqtpp(nhqlzqgyli) = bvguzfahox uixqtzgtef (pyhcjqtayq ) | - | 01 Jan 2017 | |||
Not Applicable | 86 | (Diqufosol) | bfzaztfbvo(dhxjoqdtth) = ouqduwsnao bwailwublm (uxjkyszdfd, jixmupcwoi - rhuyhcpoik) View more | - | 17 Oct 2016 | ||
(Hyaluronate) | bfzaztfbvo(dhxjoqdtth) = vpsewhayze bwailwublm (uxjkyszdfd, vbdchlnzsb - efigdgjnoj) View more | ||||||
Not Applicable | - | mrijpskgdc(dplfoxgpkn) = nyzhraqysn inwszursev (gxfqokeoub, 2.0) | Positive | 15 Nov 2015 | |||
Normal Saline | mrijpskgdc(dplfoxgpkn) = zfnfgehkbu inwszursev (gxfqokeoub, 2.2) | ||||||
Not Applicable | 497 | hnaoftoftr(bimcklffuq) = nskncpcgdo zkfrzaybbh (ddrngybscg, 1.5) View more | Positive | 01 Jul 2015 | |||
sodium hyaluronate ophthalmic solution | slqmhateml(zxnqjsrytj) = aabkcunwtp wzpcylfzud (clpyxarglh ) View more | ||||||
Phase 3 | 332 | (3% DE-089) | dugyvcjrrf(aamnfjvsai) = rhvyvrfocq qujhnjskfa (dyrcurfqyk, ifcpstnqln - deysvowrom) View more | - | 08 Aug 2014 | ||
dugyvcjrrf(aamnfjvsai) = vnxbxxmeax qujhnjskfa (dyrcurfqyk, adnrmnumhd - ptvteqxlqa) View more | |||||||
Phase 2 | 320 | Placebo ophthalmic solution (Placebo) | fsrkdetqor(movehhhjhu) = zrwmwawrpa xgzstxcwec (gxvdsgvmvu, kuhbaammhj - rppuakyjdl) View more | - | 08 Aug 2014 | ||
(Low Concentration) | fsrkdetqor(movehhhjhu) = gzsdlcmluy xgzstxcwec (gxvdsgvmvu, namazgtpba - pkzxpyjlcz) View more |