Last update 19 Sep 2024

GEN-1044

Overview

Basic Info

Drug Type
Bispecific T-cell Engager (BiTE)
Synonyms
Target
Mechanism
5T4 modulators(Trophoblast glycoprotein modulators), CD3 modulators(T cell surface glycoprotein CD3 modulators)
Therapeutic Areas
Active Indication
Originator Organization
Active Organization
Inactive Organization
Drug Highest PhasePhase 2
First Approval Date-
Regulation-

R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Metastatic Solid TumorPhase 2
ES
15 Jul 2020
NeoplasmsPhase 2--
Esophageal CarcinomaDiscovery
DK
15 Jul 2020
Esophageal CarcinomaDiscovery
US
15 Jul 2020
Esophageal CarcinomaDiscovery
ES
15 Jul 2020
Esophageal CarcinomaDiscovery
IL
15 Jul 2020
Uterine NeoplasmsDiscovery
IL
15 Jul 2020
Uterine NeoplasmsDiscovery
US
15 Jul 2020
Uterine NeoplasmsDiscovery
ES
15 Jul 2020
Uterine NeoplasmsDiscovery
DK
15 Jul 2020
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
48
(GEN1044 Doses 0.3/3/3 mg)
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-
01 Feb 2023
(GEN1044 Doses 1/3/10 mg)
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Approval

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Regulation

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