Last update 21 Nov 2024

ABX-002

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Target
Mechanism
THR-β agonists(Thyroid hormone receptor beta-1 agonists)
Inactive Indication-
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
RegulationOrphan Drug (US)
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Structure

Molecular FormulaC19H21Cl2NO3
InChIKeyCQELSEDWYWTMDG-UHFFFAOYSA-N
CAS Registry2156649-32-8

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Depressive Disorder, MajorPhase 2-16 Sep 2024
Bipolar DisorderPhase 1--
Bipolar and Related DisordersIND Approval
US
22 Oct 2024
AdrenoleukodystrophyPreclinical
US
03 May 2022
Multiple SclerosisPreclinical
US
03 May 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Biospace
ManualManual
Phase 1
48
(SAD)
(bofczdpyll) = ABX-002 demonstrated acceptable, dose proportional PK across both SAD and MAD lyonxmiydt (uimfevvrvl )
Positive
07 Nov 2023
placebo
(SAD)
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Approval

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Regulation

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