Last update 03 Sep 2025

PM1300

Overview

Basic Info

Drug Type
Antibody drug conjugate (ADC)
Synonyms
BNT-3212, PM1300
Target
EGFR x HER3
Action
antagonists
Mechanism
EGFR antagonists(Epidermal growth factor receptor erbB1 antagonists), HER3 antagonists(Receptor tyrosine-protein kinase erbB-3 antagonists)
Therapeutic Areas
Neoplasms
Active Indication
Advanced Malignant Solid NeoplasmLocally Advanced Malignant Solid NeoplasmNeoplasms
Inactive Indication-
Originator Organization
Biotheus, Inc.Biotheus, Inc.
Active Organization
Biotheus, Inc.Biotheus, Inc.
BioNTech SEBioNTech SEZhuhai Pumis Biotechnology Co., Ltd.
+ [1]
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1/2
First Approval Date-
Regulation-
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Structure/Sequence

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Related

100 Clinical Results associated with PM1300
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100 Translational Medicine associated with PM1300
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100 Patents (Medical) associated with PM1300
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100 Deals associated with PM1300
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Malignant Solid NeoplasmPhase 2
China
BioNTech (Shanghai) Pharmaceuticals Co., Ltd.
20 Aug 2025
Advanced Malignant Solid NeoplasmPhase 2
China
Zhuhai Pumis Biotechnology Co., Ltd.
20 Aug 2025
Advanced Malignant Solid NeoplasmPhase 2
Australia
BioNTech (Shanghai) Pharmaceuticals Co., Ltd.
20 Aug 2025
Advanced Malignant Solid NeoplasmPhase 2
Australia
Zhuhai Pumis Biotechnology Co., Ltd.
20 Aug 2025
Locally Advanced Malignant Solid NeoplasmPhase 2-
BioNTech SEBioNTech SE
01 Aug 2025
NeoplasmsPreclinical
China
Biotheus, Inc.Biotheus, Inc.
22 Mar 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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