Last update 20 Jun 2024

Xanthohumol

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
DGAT
Mechanism
SARS-CoV-2 Mpro inhibitors(SARS-CoV-2 main protease inhibitors)
Therapeutic Areas
Active Indication
Inactive Indication
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-

Structure

Molecular FormulaC21H22O5
InChIKeyORXQGKIUCDPEAJ-YRNVUSSQSA-N
CAS Registry6754-58-1

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Crohn DiseasePhase 2
US
01 Oct 2020
NeoplasmsPhase 1--
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
-
30
Placebo oral capsule
(Placebo Oral Capsule)
lboflxuxst(bzkpyvreqx) = jfeejqpkxz ybvbegvjnv (prdbkubzao, owsslqwgoo - oyvprwiiqf)
-
11 Jan 2022
(Xanthohumol)
lboflxuxst(bzkpyvreqx) = dnzbodeybl ybvbegvjnv (prdbkubzao, tsaorolwlf - ejujzzgxmb)
Not Applicable
-
rdyyvstcas(vycrlzllsk) = Treatment with Xn-encapsulating PLGA NPs resulted in a statistically significant reduction of corneal fluorescein staining from day 15 to day 26 ( P < 0.05), while empty NPs had no effect (P = 0.25) ymjvtmbwjw (hzzdsiillk )
Positive
01 Jun 2020
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Regulation

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