Last update 20 Jun 2024

Clobetasol Propionate/Tretinoin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Compound Clobetasol Propionate Ointment, 丙酸氯倍他索/维A酸, 金纽尔
Target
GR x RARα x RARβ2 x RARγ
Mechanism
GR agonists(Glucocorticoid receptor agonists), RARα agonists(Retinoic acid receptor alpha agonists), RARβ2 agonists(Retinoic acid receptor beta agonists)
Therapeutic Areas
Immune System DiseasesSkin and Musculoskeletal Diseases
Active Indication
Psoriasis
Inactive Indication-
Originator Organization
Sinomune Pharmaceutical Co., Ltd.Sinomune Pharmaceutical Co., Ltd.
Active Organization
Sinomune Pharmaceutical Co., Ltd.Sinomune Pharmaceutical Co., Ltd.
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
CN (21 Jan 2004),
Psoriasis
Regulation-
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Structure

Molecular FormulaC25H32ClFO5
InChIKeyCBGUOGMQLZIXBE-XGQKBEPLSA-N
CAS Registry25122-46-7
View All Structures (2)

Related

5
Clinical Trials associated with Clobetasol Propionate/Tretinoin
NCT02573883 / CompletedPhase 3IIT
A Randomized Trial of Clobetasol Propionate Versus Fractionated CO2 Laser for the Treatment of Lichen Sclerosus (CuRLS)
NCT02733874 / CompletedPhase 4IIT
A Trial That Compound Clobetasol Propionate Ointment Treats Patients With Mild to Moderate Psoriasis Vulgaris.
NCT02492373 / CompletedNot ApplicableIIT
Effect of Topical Corticosteroids on the Incidence of Postinflammatory Hyperpigmentation Following Q-switched Nd:YAG 532 nm Laser for Treatment of Facial Lentigines - A Pilot Study
100 Clinical Results associated with Clobetasol Propionate/Tretinoin
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100 Translational Medicine associated with Clobetasol Propionate/Tretinoin
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100 Patents (Medical) associated with Clobetasol Propionate/Tretinoin
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100 Deals associated with Clobetasol Propionate/Tretinoin
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External Link

KEGGWikiATCDrug Bank
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D05
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R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Psoriasis
CN
Sinomune Pharmaceutical Co., Ltd.
21 Jan 2004
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Clinical Result

Indication
Phase
Evaluation
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Study
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Approval

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Regulation

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