Last update 21 Nov 2024

AMG-337

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Target
Mechanism
c-Met inhibitors(Hepatocyte growth factor receptor inhibitors)
Originator Organization
Inactive Organization
Drug Highest PhasePhase 2
First Approval Date-
RegulationSpecial Review Project (CN)
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Structure

Molecular FormulaC23H22FN7O3
InChIKeyDWHXUGDWKAIASB-CQSZACIVSA-N
CAS Registry1173699-31-4

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Adenocarcinoma of EsophagusPhase 2--
Adenocarcinoma of EsophagusPhase 2--
Gastroesophageal junction adenocarcinomaPreclinical
AU
01 Feb 2014
Gastroesophageal junction adenocarcinomaPreclinical
FR
01 Feb 2014
Gastroesophageal junction adenocarcinomaPreclinical
RU
01 Feb 2014
Gastroesophageal junction adenocarcinomaPreclinical
HU
01 Feb 2014
Gastroesophageal junction adenocarcinomaPreclinical
GB
01 Feb 2014
Gastroesophageal junction adenocarcinomaPreclinical
IT
01 Feb 2014
Gastroesophageal junction adenocarcinomaPreclinical
CL
01 Feb 2014
Stomach CancerPreclinical
RU
09 Jan 2014
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
8
nsazuvtwep(nqhjbtzuvm) = xmlisthcvk bjprubrqbx (cvhyzhqmnk, vvyvtmncav - oqkpmuhltg)
-
24 May 2024
Phase 2
60
(MET-amplified G/GEJ/E adenocarcinoma)
(wyfxapzith) = siygufcvmr kooodqodlr (aajkklsalp )
Positive
15 Apr 2019
(other MET-amplified solid tumors)
(wyfxapzith) = idxdbxofoq kooodqodlr (aajkklsalp )
Phase 1
111
(plpipyigyu) = lfpftrbnzk urgyxecmvj (soonkuuakq )
Positive
15 Apr 2019
Phase 1
11
(ajgltwkzfc) = iupjbiblbx yiwrylkjur (egjpqomtkq )
Positive
01 Aug 2017
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Core Patent

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Clinical Trial

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Approval

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Regulation

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