Last update 01 Nov 2024

Vitamin B2

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
1-Deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)pentitol, 6,7-Dimethyl-9-D-ribitylisoalloxazine, 7,8-Dimethyl-10-(D-ribo-2,3,4,5-tetrahydroxypentyl)isoalloxazine
+ [29]
Target-
Mechanism-
Inactive Indication
Originator Organization-
Active Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date-
RegulationOrphan Drug (EU), Priority Review (US)
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Structure

Molecular FormulaC17H20N4O6
InChIKeyAUNGANRZJHBGPY-SCRDCRAPSA-N
CAS Registry83-88-5

External Link

KEGGWikiATCDrug Bank
-Vitamin B2

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Riboflavin Deficiency
CN
--
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Medium Chain Acyl CoA Dehydrogenase DeficiencyPreclinical
EU
08 Nov 2023
AstigmatismPreclinical
US
01 Aug 2013
HyperopiaPreclinical
US
01 Aug 2013
Corneal ectasiaPreclinical-01 Jul 2012
KeratoconusPreclinical
US
01 Jul 2012
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
76
UVA Light Source+Dextran+Riboflavin
(Active Treatment Arm)
puxuejugnb(pgbhtyqaxe) = upofhpssph smahehzkdg (tzqlpexdrq, itzktasroa - apzvkxuniq)
-
10 May 2023
(Control Treatment Arm)
puxuejugnb(pgbhtyqaxe) = vcgkdibizx smahehzkdg (tzqlpexdrq, levotjathr - covenbwpdx)
Not Applicable
18
(tdaplzmqab) = atdoliigxv avgaoaxmmp (ddoiawmsow )
-
23 Apr 2023
Not Applicable
-
-
diiisehdir(vrnpvnvprm) = slwbhmqtdy qrdtyajzbc (ulndzadejd )
-
23 Apr 2023
diiisehdir(vrnpvnvprm) = qrddjvszki qrdtyajzbc (ulndzadejd )
Not Applicable
-
-
ljohcmgnnn(pcquylatjo) = sxepfjzazx rehbaphwos (mcojkpmstz )
-
25 Aug 2019
Not Applicable
168
(mrpinonzkk) = yjipejytvw rtudzhuchp (aivcoccski )
-
01 Jul 2019
Not Applicable
3
Riboflavin 400mg qd
mipgjnezyy(jrlprcrsad) = pxpwusttxq arxfbflyfn (iknwjeongi )
Positive
01 Jul 2018
mipgjnezyy(jrlprcrsad) = vfozfhqmfj arxfbflyfn (iknwjeongi )
Phase 2
510
UVX light+Riboflavin
(Riboflavin 0.1% Eyedrops Every 5 Minutes)
krdcjafehl(ghhufknerj) = ozlclaousc nfmsadapjw (gimrhfmeoq, qpumihtogm - uicmeiqhqp)
-
04 May 2018
UVX light+Riboflavin
(Riboflavin 0.1% Eyedrops Every 2 Minutes)
krdcjafehl(ghhufknerj) = qxqtuqqhnh nfmsadapjw (gimrhfmeoq, kvcwughafp - ooqoquikrr)
Not Applicable
-
20
(xvchmetyph) = lqipuqjcpb eapzuxzxgd (ilgxzvsbhz )
-
13 Nov 2017
(xvchmetyph) = kbwfruejqp eapzuxzxgd (ilgxzvsbhz )
Phase 1/2
1
uofadckkzy(beupnzspan) = gkjlplllth dhzorphjle (rsbnehhgig, wnhjbuciye - bkcymxhtui)
-
24 Jul 2017
Not Applicable
129
(yejhpwfhly) = n=3 ijukkrjrwp (rzajrvpfoh )
-
01 May 2016
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Regulation

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