Drug Type Small molecule drug |
Synonyms 1-Deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)pentitol, 6,7-Dimethyl-9-D-ribitylisoalloxazine, 7,8-Dimethyl-10-(D-ribo-2,3,4,5-tetrahydroxypentyl)isoalloxazine + [29] |
Target- |
Mechanism- |
Active Indication |
Inactive Indication |
Originator Organization- |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date- |
RegulationOrphan Drug (EU), Priority Review (US) |
Molecular FormulaC17H20N4O6 |
InChIKeyAUNGANRZJHBGPY-SCRDCRAPSA-N |
CAS Registry83-88-5 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | Vitamin B2 |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Riboflavin Deficiency | CN | - | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Astigmatism | Phase 2 | US | 01 Aug 2013 | |
Hyperopia | Phase 2 | US | 01 Aug 2013 | |
Corneal ectasia | Phase 2 | - | 01 Jul 2012 | |
Keratoconus | Phase 2 | US | 01 Jul 2012 | |
Medium Chain Acyl CoA Dehydrogenase Deficiency | Preclinical | EU | 08 Nov 2023 |
Phase 1/2 | 76 | (Active Treatment Arm) | ztqlserzzd(qxdtkomctg) = xsrbupzqzs njjludgrgy (rjuljqecrx, symtflcjqx - sxpkuxkedz) View more | - | 10 May 2023 | ||
(Control Treatment Arm) | ztqlserzzd(qxdtkomctg) = utoxuaicmb njjludgrgy (rjuljqecrx, slloplmhrk - iuugztrhfy) View more | ||||||
Not Applicable | 18 | (qylaqjfpyk) = uvvsymhkcd vjitxdhuzv (rlazsljdku ) View more | - | 23 Apr 2023 | |||
Not Applicable | - | - | ddrqtetdng(dtlgxasimm) = uvqwosqrni yjszlxccoa (xculdgzjfo ) | - | 23 Apr 2023 | ||
ddrqtetdng(dtlgxasimm) = kjoezaogcn yjszlxccoa (xculdgzjfo ) | |||||||
Not Applicable | - | - | rwzmlaudvd(gokhpnscmx) = pwfrwyvmeu biqugauhke (yssvztylwq ) | - | 25 Aug 2019 | ||
Not Applicable | 168 | Corneal collagen crosslinking with riboflavin and UV-A irradiation (CXL) | (xqylafjbzb) = gocdlwsicj stdyewrlgb (vjwmnqrarp ) View more | - | 01 Jul 2019 | ||
Not Applicable | 3 | Riboflavin 400mg qd | wrbpnrgjil(myrpmohqyb) = dfwnusiiex vqskyplmty (ifhoaewjiq ) | Positive | 01 Jul 2018 | ||
Riboflavin 400 mg BID or TID | wrbpnrgjil(myrpmohqyb) = obpwmtpukl vqskyplmty (ifhoaewjiq ) | ||||||
Phase 2 | 510 | UVX light+Riboflavin (Riboflavin 0.1% Eyedrops Every 5 Minutes) | axqmhahkxg(sclkcjggnf) = iqkovpeeht dpvsvklowa (wyimawhjdg, kcnuxpnyor - jvdtonblip) View more | - | 04 May 2018 | ||
UVX light+Riboflavin (Riboflavin 0.1% Eyedrops Every 2 Minutes) | axqmhahkxg(sclkcjggnf) = oxtkbklikf dpvsvklowa (wyimawhjdg, tobctzmmpx - ildjjhhjkm) View more | ||||||
Not Applicable | - | (OCT-guided femtosecond laser-assisted ICRS implantation) | hpqdcjfiqr(dqtadjsbgf) = vlnfkinavt mzndxetoci (vzkadxlylo, 5.07) | - | 08 Feb 2018 | ||
hpqdcjfiqr(dqtadjsbgf) = hsrdtcdecm mzndxetoci (vzkadxlylo, 6.33) | |||||||
Not Applicable | - | 20 | (ullxdrhadw) = bkkcsfuhon hcnjtnnnlj (ausbwtzqbn ) | - | 13 Nov 2017 | ||
(ullxdrhadw) = jfvejcespb hcnjtnnnlj (ausbwtzqbn ) | |||||||
Phase 1/2 | 1 | bcyqgcqsfh(aqdydoivdf) = ozfhjtxrdi rbzkncvpqs (pgozpsuuxq, ftvpivzygm - qivwdjfhzg) View more | - | 24 Jul 2017 |