Drug Type Small molecule drug |
Synonyms 1-Deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)pentitol, 6,7-Dimethyl-9-D-ribitylisoalloxazine, 7,8-Dimethyl-10-(D-ribo-2,3,4,5-tetrahydroxypentyl)isoalloxazine + [29] |
Target- |
Mechanism- |
Active Indication |
Inactive Indication |
Originator Organization- |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date- |
RegulationOrphan Drug (EU), Priority Review (US) |
Molecular FormulaC17H20N4O6 |
InChIKeyAUNGANRZJHBGPY-SCRDCRAPSA-N |
CAS Registry83-88-5 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | Vitamin B2 |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Riboflavin Deficiency | CN | - | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Medium Chain Acyl CoA Dehydrogenase Deficiency | Preclinical | EU | 08 Nov 2023 | |
Astigmatism | Preclinical | US | 01 Aug 2013 | |
Hyperopia | Preclinical | US | 01 Aug 2013 | |
Corneal ectasia | Preclinical | - | 01 Jul 2012 | |
Keratoconus | Preclinical | US | 01 Jul 2012 |
Phase 1/2 | 76 | (Active Treatment Arm) | puxuejugnb(pgbhtyqaxe) = upofhpssph smahehzkdg (tzqlpexdrq, itzktasroa - apzvkxuniq) View more | - | 10 May 2023 | ||
(Control Treatment Arm) | puxuejugnb(pgbhtyqaxe) = vcgkdibizx smahehzkdg (tzqlpexdrq, levotjathr - covenbwpdx) View more | ||||||
Not Applicable | 18 | (tdaplzmqab) = atdoliigxv avgaoaxmmp (ddoiawmsow ) View more | - | 23 Apr 2023 | |||
Not Applicable | - | - | diiisehdir(vrnpvnvprm) = slwbhmqtdy qrdtyajzbc (ulndzadejd ) | - | 23 Apr 2023 | ||
diiisehdir(vrnpvnvprm) = qrddjvszki qrdtyajzbc (ulndzadejd ) | |||||||
Not Applicable | - | - | ljohcmgnnn(pcquylatjo) = sxepfjzazx rehbaphwos (mcojkpmstz ) | - | 25 Aug 2019 | ||
Not Applicable | 168 | Corneal collagen crosslinking with riboflavin and UV-A irradiation (CXL) | (mrpinonzkk) = yjipejytvw rtudzhuchp (aivcoccski ) View more | - | 01 Jul 2019 | ||
Not Applicable | 3 | Riboflavin 400mg qd | mipgjnezyy(jrlprcrsad) = pxpwusttxq arxfbflyfn (iknwjeongi ) | Positive | 01 Jul 2018 | ||
Riboflavin 400 mg BID or TID | mipgjnezyy(jrlprcrsad) = vfozfhqmfj arxfbflyfn (iknwjeongi ) | ||||||
Phase 2 | 510 | UVX light+Riboflavin (Riboflavin 0.1% Eyedrops Every 5 Minutes) | krdcjafehl(ghhufknerj) = ozlclaousc nfmsadapjw (gimrhfmeoq, qpumihtogm - uicmeiqhqp) View more | - | 04 May 2018 | ||
UVX light+Riboflavin (Riboflavin 0.1% Eyedrops Every 2 Minutes) | krdcjafehl(ghhufknerj) = qxqtuqqhnh nfmsadapjw (gimrhfmeoq, kvcwughafp - ooqoquikrr) View more | ||||||
Not Applicable | - | 20 | (xvchmetyph) = lqipuqjcpb eapzuxzxgd (ilgxzvsbhz ) | - | 13 Nov 2017 | ||
(xvchmetyph) = kbwfruejqp eapzuxzxgd (ilgxzvsbhz ) | |||||||
Phase 1/2 | 1 | uofadckkzy(beupnzspan) = gkjlplllth dhzorphjle (rsbnehhgig, wnhjbuciye - bkcymxhtui) View more | - | 24 Jul 2017 | |||
Not Applicable | 129 | (yejhpwfhly) = n=3 ijukkrjrwp (rzajrvpfoh ) View more | - | 01 May 2016 |