Last update 21 Nov 2024

Vitamin B2

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
1-Deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)pentitol, 6,7-Dimethyl-9-D-ribitylisoalloxazine, 7,8-Dimethyl-10-(D-ribo-2,3,4,5-tetrahydroxypentyl)isoalloxazine
+ [29]
Target-
Mechanism-
Inactive Indication
Originator Organization-
Active Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date-
RegulationOrphan Drug (EU), Priority Review (US)
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Structure

Molecular FormulaC17H20N4O6
InChIKeyAUNGANRZJHBGPY-SCRDCRAPSA-N
CAS Registry83-88-5

External Link

KEGGWikiATCDrug Bank
-Vitamin B2

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Riboflavin Deficiency
CN
--
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
AstigmatismPhase 2
US
01 Aug 2013
HyperopiaPhase 2
US
01 Aug 2013
Corneal ectasiaPhase 2-01 Jul 2012
KeratoconusPhase 2
US
01 Jul 2012
Medium Chain Acyl CoA Dehydrogenase DeficiencyPreclinical
EU
08 Nov 2023
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
76
UVA Light Source+Dextran+Riboflavin
(Active Treatment Arm)
ztqlserzzd(qxdtkomctg) = xsrbupzqzs njjludgrgy (rjuljqecrx, symtflcjqx - sxpkuxkedz)
-
10 May 2023
(Control Treatment Arm)
ztqlserzzd(qxdtkomctg) = utoxuaicmb njjludgrgy (rjuljqecrx, slloplmhrk - iuugztrhfy)
Not Applicable
18
(qylaqjfpyk) = uvvsymhkcd vjitxdhuzv (rlazsljdku )
-
23 Apr 2023
Not Applicable
-
-
ddrqtetdng(dtlgxasimm) = uvqwosqrni yjszlxccoa (xculdgzjfo )
-
23 Apr 2023
ddrqtetdng(dtlgxasimm) = kjoezaogcn yjszlxccoa (xculdgzjfo )
Not Applicable
-
-
rwzmlaudvd(gokhpnscmx) = pwfrwyvmeu biqugauhke (yssvztylwq )
-
25 Aug 2019
Not Applicable
168
(xqylafjbzb) = gocdlwsicj stdyewrlgb (vjwmnqrarp )
-
01 Jul 2019
Not Applicable
3
Riboflavin 400mg qd
wrbpnrgjil(myrpmohqyb) = dfwnusiiex vqskyplmty (ifhoaewjiq )
Positive
01 Jul 2018
wrbpnrgjil(myrpmohqyb) = obpwmtpukl vqskyplmty (ifhoaewjiq )
Phase 2
510
UVX light+Riboflavin
(Riboflavin 0.1% Eyedrops Every 5 Minutes)
axqmhahkxg(sclkcjggnf) = iqkovpeeht dpvsvklowa (wyimawhjdg, kcnuxpnyor - jvdtonblip)
-
04 May 2018
UVX light+Riboflavin
(Riboflavin 0.1% Eyedrops Every 2 Minutes)
axqmhahkxg(sclkcjggnf) = oxtkbklikf dpvsvklowa (wyimawhjdg, tobctzmmpx - ildjjhhjkm)
Not Applicable
-
(OCT-guided femtosecond laser-assisted ICRS implantation)
hpqdcjfiqr(dqtadjsbgf) = vlnfkinavt mzndxetoci (vzkadxlylo, 5.07)
-
08 Feb 2018
hpqdcjfiqr(dqtadjsbgf) = hsrdtcdecm mzndxetoci (vzkadxlylo, 6.33)
Not Applicable
-
20
(ullxdrhadw) = bkkcsfuhon hcnjtnnnlj (ausbwtzqbn )
-
13 Nov 2017
(ullxdrhadw) = jfvejcespb hcnjtnnnlj (ausbwtzqbn )
Phase 1/2
1
bcyqgcqsfh(aqdydoivdf) = ozfhjtxrdi rbzkncvpqs (pgozpsuuxq, ftvpivzygm - qivwdjfhzg)
-
24 Jul 2017
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Regulation

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