Last update 01 Nov 2024

Cefotetan Disodium

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(6R,7S)-7-(4-(carbamoylcarboxymethylene)-1,3-dithiethane-2-carboxamido)-7-methoxy-3-(((1-methyl-1H-tetrazol-5- yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2- carboxylic acid, Cefotetan disodium (USP), Cefotetan sodium (JAN)
+ [6]
Target
Mechanism
PBPs inhibitors(Bacterial penicillin-binding protein inhibitors), Cell wall inhibitors
Originator Organization
Drug Highest PhaseApproved
First Approval Date
US (27 Dec 1985),
Regulation-
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Structure

Molecular FormulaC17H17N7NaO8S4
InChIKeyBTOFDTWBLNLGSY-DWUNWFSHSA-N
CAS Registry74356-00-6

External Link

R&D Status

Approved
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IndicationCountry/LocationOrganizationDate
Infectious Diseases
US
27 Dec 1985
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Bacterial InfectionsPhase 2
CN
21 Feb 2017
Genitourinary tract infectionPhase 2
CN
12 Apr 2012
Respiratory Tract InfectionsPhase 2
CN
12 Apr 2012
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
-
1,002
gaopxhgxee(vxyrcivlox) = the overall incidence of Clostridium difficile infection was 1.7% in the ertapenem group and 0.6% in the cefotetan group (P=0.22) jsbtlrpccz (hjnehurcja )
-
21 Dec 2006
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Approval

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Regulation

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