HRS-1301

Part 1: Primary objective: To evaluate the safety and tolerability of a single dose of HRS-1301 in healthy subjects. Secondary objective: To evaluate the PK characteristics of a single dose of HRS-1301 in healthy subjects; To evaluate the PD characteristics of a single dose of HRS-1301 in healthy subjects; To evaluate the effects of food on the PK and PD characteristics of HRS-1301. Exploratory objective: To evaluate the effects of HRS-1301 on the QT interval in healthy subjects; To evaluate the metabolic characteristics of HRS-1301 in healthy subjects. Part 2: Primary objective: To evaluate the safety and tolerability of multiple doses of HRS-1301 in healthy subjects with elevated LDL-C. Secondary objective: To evaluate the PK characteristics of multiple doses of HRS-1301 in healthy subjects with elevated LDL-C; To evaluate the PD characteristics of multiple doses of HRS-1301 in healthy subjects with elevated LDL-C. Exploratory objectives: To evaluate the relationship between HRS-1301 exposure and effect; to evaluate the metabolic characteristics of HRS-1301 in healthy subjects with elevated LDL-C.