Last update 31 May 2025

XH-S003

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
XH S003, XH-S003, XHS003
Target
CFB
Action
modulators
Mechanism
CFB modulators(Complement factor B modulators)
Therapeutic Areas
Immune System DiseasesUrogenital DiseasesHemic and Lymphatic Diseases+ [1]
Active Indication
Hemoglobinuria, ParoxysmalGlomerulonephritis, IGA
Inactive Indication-
Originator Organization
Zhejiang Xinghao Pengbo Pharmaceutical Co., Ltd.
Active Organization
Shanghai Fosun Pharmaceutical (Group) Co., Ltd.Shanghai Fosun Pharmaceutical (Group) Co., Ltd.Zhejiang Xinghao Pengbo Pharmaceutical Co., Ltd.
Inactive Organization-
License Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Related

4
Clinical Trials associated with XH-S003
NCT06978699
/ RecruitingPhase 2
A Multicenter, Randomized, Single-blind Phase II Study Evaluating the Efficacy and Safety of XH-S003 Capsules in Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH)
CTR20244548
/ RecruitingPhase 2
一项在原发性IgA肾病患者中评价XH-S003的安全性和有效性的多中心、单臂、开放研究
[Translation] A multicenter, single-arm, open-label study to evaluate the safety and efficacy of XH-S003 in patients with primary IgA nephropathy
NCT05946876
/ CompletedPhase 1
A Phase I Study to Assess the Safety, Tolerability, Pharmacokinetics of XH-S003 After Single and Multiple Ascending Doses, Plus the Evaluation of Food Effects in Healthy Volunteers
100 Clinical Results associated with XH-S003
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100 Translational Medicine associated with XH-S003
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100 Patents (Medical) associated with XH-S003
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100 Deals associated with XH-S003
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hemoglobinuria, ParoxysmalPhase 2
China
Shanghai Fosun Pharmaceutical (Group) Co., Ltd.Shanghai Fosun Pharmaceutical (Group) Co., Ltd.
30 Apr 2025
Glomerulonephritis, IGAPhase 2
China
Zhejiang Xinghao Pengbo Pharmaceutical Co., Ltd.
26 Dec 2024
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Clinical Result

Indication
Phase
Evaluation
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Core Patent

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Clinical Trial

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Approval

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Regulation

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