[Translation] Phase Ib clinical trial of the safety, tolerability, pharmacokinetic and pharmacodynamic characteristics of XH-S004 tablets after repeated administration in patients with chronic obstructive pulmonary disease (COPD)
主要目的:在COPD患者中,评价XH-S004片的安全性和耐受性。
次要目的:在COPD患中,评价XH-S004片的药代动力学(PK)特征;在COPD患者中,评价XH-S004片主要的药效动力学(PD)指标特征;评价XH-S004片对COPD患者的肺功能指标的影响。
[Translation] Primary objective: To evaluate the safety and tolerability of XH-S004 tablets in COPD patients.
Secondary objectives: To evaluate the pharmacokinetic (PK) characteristics of XH-S004 tablets in COPD patients; To evaluate the main pharmacodynamic (PD) index characteristics of XH-S004 tablets in COPD patients; To evaluate the effect of XH-S004 tablets on lung function indicators in COPD patients.