Last update 26 Dec 2024

Ruserontinib

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
SKLB 1028, SKLB-1028
Mechanism
ABL inhibitors(Abl family tyrosine kinases inhibitors), EGFR antagonists(Epidermal growth factor receptor erbB1 antagonists), FLT3 inhibitors(Tyrosine-protein kinase receptor FLT3 inhibitors)
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 3
First Approval Date-
RegulationSpecial Review Project (CN)
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Structure

Molecular FormulaC24H29N9
InChIKeyWSOHOUHPUOAXIN-UHFFFAOYSA-N
CAS Registry1350544-93-2

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acute Myeloid Leukemia with FLT3/ITD MutationPhase 3
CN
24 Mar 2021
FLT3 positive Acute Myeloid LeukemiaPhase 3
CN
24 Mar 2021
FLT3 positive Acute Myeloid LeukemiaPhase 3
CN
24 Mar 2021
Refractory acute myeloid leukemiaPhase 2
CN
01 Jul 2019
Advanced Malignant Solid NeoplasmPhase 1
CN
29 Sep 2021
Advanced Malignant Solid NeoplasmPhase 1
CN
29 Sep 2021
Relapsing acute myeloid leukemiaPhase 1
CN
01 May 2016
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
28
hlbehqahar(bzunmnfzla) = pyrexia 67.9%, diarrhoea 64.3%, asthenia 53.6%, dizziness 50.0% rxxyvfwdcs (oxzawnndxy )
Positive
13 Nov 2019
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Regulation

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