Last update 01 Nov 2024

Ruserontinib

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Mechanism
ABL inhibitors(Abl family tyrosine kinases inhibitors), EGFR antagonists(Epidermal growth factor receptor erbB1 antagonists), FLT3 inhibitors(Tyrosine-protein kinase receptor FLT3 inhibitors)
+ [1]
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 3
First Approval Date-
RegulationSpecial Review Project (CN)
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Structure

Molecular FormulaC24H29N9
InChIKeyWSOHOUHPUOAXIN-UHFFFAOYSA-N
CAS Registry1350544-93-2

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acute Myeloid Leukemia with FLT3/ITD MutationPhase 3
CN
24 Mar 2021
FLT3 positive Acute Myeloid LeukemiaPhase 3
CN
24 Mar 2021
FLT3 positive Acute Myeloid LeukemiaPhase 3
CN
24 Mar 2021
Advanced Malignant Solid NeoplasmPhase 1
CN
29 Sep 2021
Advanced Malignant Solid NeoplasmPhase 1
CN
29 Sep 2021
Refractory acute myeloid leukemiaDiscovery
CN
01 Jul 2019
Relapsing acute myeloid leukemiaDiscovery
CN
01 May 2016
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
28
(hdasyovdbd) = pyrexia 67.9%, diarrhoea 64.3%, asthenia 53.6%, dizziness 50.0% pfhadrxkwb (mlziewupue )
Positive
13 Nov 2019
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Approval

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Regulation

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