Last update 21 Nov 2024

Trastuzumab botidotin

Overview

Basic Info

Drug Type
Antibody drug conjugate (ADC)
Synonyms
博度曲妥珠单抗
+ [1]
Mechanism
HER2 antagonists(Receptor protein-tyrosine kinase erbB-2 antagonists), Tubulin inhibitors
Drug Highest PhaseNDA/BLA
First Approval Date-
Regulation-
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Structure

Molecular FormulaC11H22N4O4
InChIKeyAGGWFDNPHKLBBV-YUMQZZPRSA-N
CAS Registry159858-33-0
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
HER2 Positive Breast CancerNDA/BLA
CN
11 May 2023
Bladder CancerPreclinical
US
16 Jul 2018
HER2-positive gastric cancerPreclinical
US
16 Jul 2018
Liver CancerPreclinical
US
16 Jul 2018
Mucoepidermoid CarcinomaPreclinical
US
16 Jul 2018
Palatal NeoplasmsPreclinical
US
16 Jul 2018
Rectal CancerPreclinical
US
16 Jul 2018
Recurrent CarcinomaPreclinical
US
16 Jul 2018
Salivary gland carcinomaPreclinical
US
16 Jul 2018
Tonsillar NeoplasmsDiscovery
US
16 Jul 2018
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
58
(bfmeqqjnqp) = spouduptjh ltslycsmyi (cepeyohpgr, 51.59 - 89.77)
-
02 Jun 2022
Phase 1
57
(kquaewelrq) = 19.3% uepintbxsg (prmwvvugen )
Positive
28 May 2021
Phase 1/2
35
(xgbzdwffop) = Keratitis, Decreased appetite, Dry eye, Vision blurred etc lerpprhrah (oycjugugrq )
Positive
29 May 2020
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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Accelerate your research with the latest regulatory approval information.

Regulation

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