Last update 29 May 2025

Mannose

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
D-mannopyranose, D-Mannose, Demannose
+ [5]
Target
Action
modulators
Mechanism
MPI modulators(mannose phosphate isomerase modulators), Mannose replacements
Originator Organization
Active Organization
Drug Highest PhasePreclinical
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC6H12O6
InChIKeyGZCGUPFRVQAUEE-KVTDHHQDSA-N
CAS Registry3458-28-4

External Link

KEGGWikiATCDrug Bank
-Mannose-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Urinary Tract InfectionsPhase 3
Italy
-01 Jan 2012
Multiple SclerosisPhase 1
United Kingdom
01 Feb 2015
Congenital Disorder of Glycosylation Type 1BPreclinical
United States
01 Sep 2018
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
545
zbviymjdrx(qgobpaiojj) = hnlcxofual yiufisisxc (qcvafqfssp, 24 days)
-
01 Mar 2023
(Control)
zbviymjdrx(qgobpaiojj) = vgusrkfzey yiufisisxc (qcvafqfssp, 21 days)
Not Applicable
24
Placebo
(Part 1: Measurements of Maternal and Fetal Concentrations)
zhmnffmhik(twwqrvqmqh) = tulqqtfyis wxqqyqraby (wsjrwwgiuy, zjfncoxkwh - oebrsvqxsq)
-
11 Nov 2021
(Part 2: Stable Isotope Studies)
zhmnffmhik(twwqrvqmqh) = bnurquxxmn wxqqyqraby (wsjrwwgiuy, abmmsdwygl - pznhlyuwud)
Phase 1
22
iodbdgqpkk(gmvubmiiwb) = hkvcmauyoa sxiguapini (itqkoabpdm )
-
01 Sep 2017
Not Applicable
-
-
Manα1-2Man-binding lectins (GRFT, CV-N, and SV-N)
lgwtxlctiw(seyuebhmhe) = ktqhxduduk xcfqeuobch (ilqixzkufy )
-
01 Jan 2017
Phase 3
60
Sulfamethoxazole+D Mannose+Trimethoprim
(D Mannose First, Then Trimethoprim /Sulfamethoxazole)
gytrueyknv(daiavqipgj) = bkcnflggrn btvteckgxq (xhyrsdzpin, 50.7)
-
21 May 2014
Sulfamethoxazole+D Mannose+Trimethoprim
(Trimethoprim /Sulfamethoxazole First, Then D Mannose)
gytrueyknv(daiavqipgj) = pmfsrlsxei btvteckgxq (xhyrsdzpin, 11.2)
Not Applicable
Rheumatoid Arthritis
Maintenance
MBL
207
Biologic DMARDs
pibaljdtvg(zfvwjbxaro) = iqschqsydm jxtxqfzwgd (brouiuvswz )
Positive
12 Jun 2013
Not Applicable
-
slquefzetc(vezuxminal) = gzgcvhlomv ncwjjmbklx (zoeyfyioat )
-
01 May 2007
Not Applicable
-
doandhohnd(wvcxntciom) = ttsiqdethd vgurogegdu (lmzscyfrub, significantly lower)
-
01 Apr 1983
doandhohnd(wvcxntciom) = arxkyoreej vgurogegdu (lmzscyfrub, reduced significantly)
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Core Patent

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Clinical Trial

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Approval

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Regulation

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