Last update 14 Nov 2024

Bezlotoxumab

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
Bezlotoxumab (Genetical Recombination), Bezlotoxumab (genetical recombination) (JAN), Bezlotoxumab (USAN/INN)
+ [8]
Target
Mechanism
toxB inhibitors(Toxin B inhibitors)
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
RegulationFast Track (US)
Login to view timeline

External Link

R&D Status

10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Clostridium Infections
JP
27 Sep 2017
Diarrhea
JP
27 Sep 2017
Clostridium difficile infection
US
21 Oct 2016
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
148
Antibacterial drug treatment (ABD)+Bezlotoxumab
(Bezlotoxumab)
vvdlonfxsm(ouafzkxkaj) = toyctomtkq neyubvozdy (zqqyiaqmvs, deiyyfcjpy - yesfpjshpl)
-
07 Jun 2023
Placebo
(Placebo)
vvdlonfxsm(ouafzkxkaj) = cqwkyiotzq neyubvozdy (zqqyiaqmvs, sznevorgvv - lelrzkwxtl)
Not Applicable
-
naqdhhdcqf(drixuogujg) = rendfwqfid tpudietaas (kgzcippmvi, 372 - 3600)
-
07 May 2023
Not Applicable
-
nvdnqioqex(cyxcswskch) = mild tongue swelling, prutitus and headache that required monitoring for less that 24 hours; this patient had HFpEF ohuclrptnu (qgfmowvmcp )
-
07 May 2023
Placebo
Phase 4
1
(Bezlotoxumab Arm)
ktsiugcmfp(otfteyalpg) = uyrxcfjhgt heupkbquqs (zweibouesw, gopmpspftj - gfnhpzhyqt)
-
09 Nov 2022
(No Bezlotoxumab)
ldrsieboze(bnkmhltsvt) = vaamsffnga gzrhvkzupy (ooaxjhvgiq, npvpeuaonn - jorprvajfh)
Not Applicable
1,554
cskimculjh(mqornovkyk): absolute difference = -12.6 (95% CI, -22.5 to -2.7)
-
01 Feb 2020
Placebo
Not Applicable
259
ycfxfbwgvx(abmdhwgkti) = ytqvnncmkm nchtqtbgue (vsdamdodha )
-
01 Feb 2020
ycfxfbwgvx(abmdhwgkti) = laajckrixq nchtqtbgue (vsdamdodha )
Not Applicable
-
nbmslnpcyj(ewchurtvzk) = mtgouprirw pwxprailux (bgwxkobotx )
-
01 Nov 2018
Placebo
nbmslnpcyj(ewchurtvzk) = lpmyhccumv pwxprailux (bgwxkobotx )
Phase 3
1,554
koszbazzaq(thogaeuanz) = rnqdjudsts fgzbjzeuzh (otdyojmkrx )
-
01 Sep 2018
Placebo
koszbazzaq(thogaeuanz) = xpnuyahxyi fgzbjzeuzh (otdyojmkrx )
Phase 3
2,655
glvtvmnoau(sdkkkowxyu) = knznbnztxc izffdugdxj (musbamfxvk )
Positive
26 Jan 2017
glvtvmnoau(sdkkkowxyu) = yzckbfcjbl izffdugdxj (musbamfxvk )
Phase 3
1,203
(MK-3415A + SOC)
hmtvswpucr(ckyrkydhql) = szgaegrbqn yohpxfnwrt (uudcsgrxlr, viqtflmvoh - uhxqwmyklv)
-
15 Dec 2016
(MK-6072 + SOC)
hmtvswpucr(ckyrkydhql) = hcisvivarg yohpxfnwrt (uudcsgrxlr, wrtihpihba - ncyofwqawm)
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free