Pontmestrocel

Patients with blood diseases with high risk of GVHD who need hematopoietic stem cell transplantation were selected as subjects. The clinical and laboratory indicators of simple hematopoietic stem cell transplantation and co-transplantation of bone marrow primitive mesenchymal stem cells and hematopoietic stem cells were compared. The main purpose was to observe whether combined bone marrow primitive mesenchymal stem cell transplantation can reduce the incidence and severity of GVHD, and at the same time observe the impact on hematopoietic reconstruction and whether it can improve the success rate of transplantation. Safety was further evaluated.