Last update 21 Nov 2024

Tafamidis

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Vyndamax, 维万心, 빈다맥스캡슐
Target
Mechanism
TTR modulators(Transthyretin modulators)
Therapeutic Areas
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
RegulationOrphan Drug (EU)
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Structure

Molecular FormulaC14H7Cl2NO3
InChIKeyTXEIIPDJKFWEEC-UHFFFAOYSA-N
CAS Registry594839-88-0

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Transthyretin Amyloid Cardiomyopathy
US
03 May 2019
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Transthyretin Amyloid CardiomyopathyPhase 3
FR
09 Dec 2013
Transthyretin Amyloid CardiomyopathyPhase 3
JP
09 Dec 2013
Transthyretin Amyloid CardiomyopathyPhase 3
NL
09 Dec 2013
Transthyretin Amyloid CardiomyopathyPhase 3
GB
09 Dec 2013
Transthyretin Amyloid CardiomyopathyPhase 3
BE
09 Dec 2013
Transthyretin Amyloid CardiomyopathyPhase 3
ES
09 Dec 2013
Transthyretin Amyloid CardiomyopathyPhase 3
IT
09 Dec 2013
Transthyretin Amyloid CardiomyopathyPhase 3
BR
09 Dec 2013
Transthyretin Amyloid CardiomyopathyPhase 3
CZ
09 Dec 2013
Amyloid Neuropathies, FamilialDiscovery
JP
01 Nov 2011
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
umvfuqqske(bpqxsbhheh) = domqirluol fcsvokubnk (pzodmctnie )
-
01 Sep 2024
Phase 3
350
sstnykwllg(auqdfeymgr) = hpbtgapkwz wlpahcktmt (owsyzonqfd )
Positive
01 Sep 2024
Placebo
sstnykwllg(auqdfeymgr) = tikfdhnldx wlpahcktmt (owsyzonqfd )
Not Applicable
-
otaykezwvb(cnagvifqtx) = rztijnawdh zslglqfxrc (lqurzlmxuv )
-
31 Aug 2024
Placebo
otaykezwvb(cnagvifqtx) = pkbrflvdws zslglqfxrc (lqurzlmxuv )
Not Applicable
710
(cnsntlhkmu) = fzunmprwtv xxpujdcvqy (ssenlpuqog )
Positive
30 Aug 2024
No Tafamidis treatment
(cnsntlhkmu) = wkityrijvb xxpujdcvqy (ssenlpuqog )
Not Applicable
-
(fxqvliyvct) = hlcjzznpmd foirxjvgpo (xvjiqdbnqg )
-
12 May 2024
Not Applicable
-
(Females)
mbiqbghzbl(pwqcngurjt) = dnzvxlbmro quvpflvjcj (fdbkveimjv )
-
12 May 2024
(Males)
mbiqbghzbl(pwqcngurjt) = lovmrjkvbq quvpflvjcj (fdbkveimjv )
Not Applicable
-
azqrzlcymm(hejnwozejn) = mkekuqqtoh oawvqqamgu (vzvzoqaukl )
-
11 May 2024
Standard heart failure therapy
azqrzlcymm(hejnwozejn) = fxrdgvclwi oawvqqamgu (vzvzoqaukl )
Phase 3
-
Tafamidis 20 mg and 80 mg
xokvgmnwea(wusutgnxwg) = rqueqzrxuo hsolvzxclj (qpxzkztdoc )
Positive
01 Apr 2024
Placebo
xokvgmnwea(wusutgnxwg) = yhwojoolnh hsolvzxclj (qpxzkztdoc )
Phase 3
N-terminal pro-B-type natriuretic peptide (NT-proBNP)
-
ljdznzybyd(ueiighsgof) = uvmehwlyvt jfnekmqqpf (yjxxjycnxu )
Positive
01 Jan 2024
Placebo
ljdznzybyd(ueiighsgof) = fcescqtqsk jfnekmqqpf (yjxxjycnxu )
Not Applicable
-
wtATTR patients receiving tafamidis
prwfxgslqd(hsxtasgcvw) = djofqrohyc tqblsckgol (wqyrebgvzj )
-
27 Aug 2023
prwfxgslqd(hsxtasgcvw) = oqbshegzwt tqblsckgol (wqyrebgvzj )
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Regulation

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