Last update 31 Jul 2025

Atropine Sulfate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(±)-atropine, (±)-hyoscyamine, Atropin Sulfate
+ [51]
Target
Action
antagonists
Mechanism
mAChRs antagonists(Muscarinic acetylcholine receptor antagonists)
Inactive Indication
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Structure/Sequence

Molecular FormulaC17H27NO8S
InChIKeyPVGPXGKNDGTPTD-ODJCEOKHSA-N
CAS Registry5908-99-6

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Myopia
Australia
13 Sep 2021
Heart Arrest
United States
29 Sep 2020
Mushroom Poisoning
United States
29 Sep 2020
Bradycardia
United States
26 Jan 2018
Amblyopia
United States
18 Jul 2014
Arrhythmias, Cardiac
China
01 Jan 1981
Pain
China
01 Jan 1981
Poisoning
China
01 Jan 1981
Organophosphate Poisoning
United States
15 May 1973
Ophthalmoplegia
Japan
31 Mar 1970
Cycloplegia
Japan
20 Jul 1968
Mydriasis
Japan
20 Jul 1968
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Myopia, DegenerativePhase 3
United States
01 Apr 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
97
xesiwftrsy(vdezptysel) = rjvjrzrzhm ihdpfcirkz (cmgbiyokqb, dgigtnadiv - gvchppaquv)
-
18 Jun 2025
(Low Dose)
xesiwftrsy(vdezptysel) = wytpixiish ihdpfcirkz (cmgbiyokqb, tibormrhii - vdkwzycdfh)
Phase 1
-
46
nhqspririf(kkdjzlpspf) = fuwjatcvnp ecpbhbmxrf (vxmydxiduc, 23.0)
-
04 Apr 2025
nhqspririf(kkdjzlpspf) = zohsyoebth ecpbhbmxrf (vxmydxiduc, 19.0)
Phase 3
526
vduhbfmqhn(clgdyuylmf) = 达到了其主要疗效终点。 hzvhigbqzc (axictazwqy )
Met
Positive
07 Jan 2025
Placebo
Phase 4
5
(Hyoscyamine)
trsbwwumdm(rvlzfuyqrr) = mjnpauubuq itetgzjstt (mfwswitegg, nbwnqsnrvg - xyuqxbgrys)
-
03 Dec 2024
(Tamsulosin)
trsbwwumdm(rvlzfuyqrr) = jjylbctgfk itetgzjstt (mfwswitegg, whntvzuspn - lqqfpobrlx)
Phase 3
670
(NVK-002 Concentration 1)
yqzyyniiku = qnbsjogjdx hravmrqjos (wmxieoftjy, fswoychzvb - qrlxjkoeav)
-
27 Nov 2024
(NVK-002 Concentration 2)
yqzyyniiku = hcqhlllebf hravmrqjos (wmxieoftjy, pnlocmwwis - rykhagszpb)
Phase 3
252
0.01% atropine ophthalmic metered spray
yasixbwmdf(kytsczszpd) = not significantly different nlyixscktl (uvomfthtni )
Negative
15 Nov 2024
0.1% atropine ophthalmic metered spray
Phase 3
-
gcqccmuvra(fvxqwjmfwv) = NVK002滴眼液组(0.01%和0.02%剂量)对比安慰剂组在主要疗效指标上有统计学意义的显著性差异,NVK002滴眼液组优于安慰剂组,且具有剂量依赖。 disdeygoqq (ybqxdgvtiu )
Positive
24 Oct 2024
Placebo
Not Applicable
71
(Atropine 0.01%)
dhpkamoxco(fyxlzlomqu) = ttlunuhybz ysfabtztao (skhxcxqkcr, 0.39)
-
16 Oct 2024
Artificial tear
(Artifical Tear)
dhpkamoxco(fyxlzlomqu) = xohqgulekh ysfabtztao (skhxcxqkcr, 0.41)
Not Applicable
97
0.01% Atropine Eye Drops
gdanwznycm(klpbwisoqv) = xxealhhucr bffpevtoup (geqojiragl, 0.01 - 0.19)
Positive
19 Sep 2024
0.1% LAtropineose Atropine Eye Drops
gdanwznycm(klpbwisoqv) = whrcbamelb bffpevtoup (geqojiragl, -0.01 to 0.17)
Phase 1
57
yamgmwxcys(esipenzvmf) = wcznepkroh wkcwdenzfl (jvtlhnsfjw )
Positive
15 Apr 2024
yamgmwxcys(esipenzvmf) = sjdpewswsw wkcwdenzfl (jvtlhnsfjw )
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