Last update 19 Apr 2025

AMG-529

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
AMG 529, AMG529
Target
ASGR1
Action
inhibitors
Mechanism
ASGR1 inhibitors(Asialoglycoprotein receptor 1 inhibitors)
Therapeutic Areas-
Active Indication-
Inactive Indication-
Originator Organization
Amgen, Inc.Amgen, Inc.
Active Organization-
Inactive Organization
Amgen, Inc.Amgen, Inc.
Drug Highest PhasePendingPhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with AMG-529
NCT03170193
/ CompletedPhase 1
A Phase 1, Randomized, Double-blind, Placebo-controlled, Ascending Single Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AMG 529 in Healthy Subjects
100 Clinical Results associated with AMG-529
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100 Translational Medicine associated with AMG-529
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100 Patents (Medical) associated with AMG-529
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100 Deals associated with AMG-529
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R&D Status

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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
NCT03170193 (CTgov)
Phase 1
-
48
Placebo
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-
05 Jul 2019
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Clinical Trial

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Approval

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Biosimilar

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Regulation

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