Last update 21 Mar 2024

ASGR1

Asialoglycoprotein receptor 1

Basic Info

Synonyms
ASGP-R 1, ASGPR 1, ASGR1
+ [5]
Introduction
Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.

Analysis

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