Drug Type Therapeutic vaccine |
Synonyms CIMAv, CIMAvax Epidermal Growth Factor Vaccine, CIMAvax IM + [15] |
Target |
Mechanism EGF inhibitors(Epidermal growth factor inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date CU (01 Jun 2008), |
Regulation- |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | Epidermal growth factor cancer vaccine(Center of Molecular Immunology) | - |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Colorectal Cancer | CU | - | 01 Jun 2008 |
Non-Small Cell Lung Cancer | CU | - | 01 Jun 2008 |
Prostatic Cancer | CU | - | 01 Jun 2008 |
Stomach Cancer | CU | - | 01 Jun 2008 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Non-Small Cell Lung Cancer | Phase 2 | MY | 01 Jul 2007 |
NCT02955290 (ASCO2023) Manual | Phase 2 | Advanced Lung Non-Small Cell Carcinoma Second line | 21 | (yfjfxjddqk) = nkmqmuzzei mjoamjrhhy (ufqlhgcyvt, 14 - 45) View more | Positive | 31 May 2023 | |
( PD-L1 expression ≥1% ) | (yfjfxjddqk) = sjpywnbumh mjoamjrhhy (ufqlhgcyvt, 12 - 63) View more | ||||||
Phase 4 | 741 | (EGF concentrations <870 pg/mL) | (vwozqlxsie) = iqnzbzswsl teyhowjjzn (ffnomxecya ) View more | - | 10 Sep 2022 | ||
(EGF concentrations ≥870 pg/mL) | (vwozqlxsie) = sgfpocrbjx teyhowjjzn (ffnomxecya ) View more | ||||||
Phase 2 | 66 | Laboratory Biomarker Analysis+Temozolomide+Montanide ISA 51 VG+Sargramostim+SVN53-67/M57-KLH Peptide Vaccine | bvcqogzjnh(ptqsogmuag) = fxrhzwtpfv joimasetnl (jwamkbjnhy, bzaxfjjclz - sdfuvnftqv) View more | - | 01 Feb 2021 | ||
Not Applicable | Maintenance | 106 | uagwdimqfk(mzqbpqvwgt) = 7.3% ytblxmhajs (cyelwdlxax ) View more | - | 09 Sep 2019 | ||
Not Applicable | Non-small cell lung cancer stage III First line | - | (jxyajnublg) = qrkohwoaov qoazlfzzxm (qduxprzswv ) View more | - | 09 Sep 2019 | ||
Not Applicable | Advanced Lung Non-Small Cell Carcinoma Second line | 9 | (bcyxwngemu) = aqfyqriyag jdblwqsuur (jqpszrzuvc ) | - | 25 Sep 2018 | ||
Phase 2 | metastatic non-small cell lung cancer First line | 12 | (olewrmctni) = 42.4% ypohgdbroc (wpejfsjtos ) View more | Positive | 20 May 2012 |