Last update 21 Nov 2024

Stiripentol

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
1-(1,3-Benzodioxol-5-yl)-4,4-dimethyl-1-penten-3-ol, 4,4-Dimethyl-1-((3,4-methylenedioxy)phenyl)-1-penten-3-ol, Diacomit Drysyrup
+ [7]
Mechanism
GABAA receptor agonists(Gamma-aminobutyric acid A receptor agonists), L-lactate dehydrogenase inhibitors(L-lactate dehydrogenase inhibitors)
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
RegulationOrphan Drug (JP), Priority Review (US)
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Structure

Molecular FormulaC14H18O3
InChIKeyIBLNKMRFIPWSOY-UHFFFAOYSA-N
CAS Registry49763-96-4

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
CDKL5 Deficiency Disorder
US
20 Aug 2018
Seizures
US
20 Aug 2018
Epilepsies, Myoclonic
NO
03 Jan 2007
Epilepsies, Myoclonic
EU
03 Jan 2007
Epilepsies, Myoclonic
IS
03 Jan 2007
Epilepsies, Myoclonic
LI
03 Jan 2007
Epilepsy, Tonic-Clonic
EU
03 Jan 2007
Epilepsy, Tonic-Clonic
LI
03 Jan 2007
Epilepsy, Tonic-Clonic
NO
03 Jan 2007
Epilepsy, Tonic-Clonic
IS
03 Jan 2007
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Primary Hyperoxaluria Type 1Phase 3-01 Aug 2024
Primary Hyperoxaluria Type 2Phase 3-01 Aug 2024
Primary hyperoxaluria type IIIPhase 3-01 Aug 2024
Chronic Kidney DiseasesPhase 1
BG
24 Jul 2023
SeizuresPreclinical
JP
06 Sep 2015
Hyperoxaluria, PrimaryDiscovery
FR
21 May 2019
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
25
nsmaacvxsa(vhpcowesjf) = kgxmfipvkh ieedtzlcdv (datehfjxed )
Positive
21 Oct 2024
Not Applicable
-
-
vmjkefjzea(dlzbafrlpc) = STP administration led to a median decrease in GTCS frequency of 84.4%, compared to 5.8% in the placebo group eogywndpdh (tuuzrgrlkc )
Positive
04 Sep 2023
Placebo
Not Applicable
-
tvloftrkgh(vxvongoeit) = ejwptkzvjw spzblmsxgi (pitmbfczzw )
Positive
26 Jun 2013
tvloftrkgh(vxvongoeit) = bdojgogeyg spzblmsxgi (pitmbfczzw )
Not Applicable
-
22
(Dravet syndrome)
rqvneckavn(gzccjsimrx) = vehkhoehca aduswtebbr (dqglkjhqau )
Negative
02 Jul 2009
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Regulation

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