Drug Type Small molecule drug |
Synonyms BMS-986310, BMS986310, ONO 4578 + [1] |
Target |
Mechanism EP4 antagonists(Prostanoid EP4 receptor antagonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhasePhase 2 |
First Approval Date- |
Regulation- |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Gastrooesophageal junction cancer | Phase 2 | JP | 06 Dec 2023 | |
Gastrooesophageal junction cancer | Phase 2 | KR | 06 Dec 2023 | |
Gastrooesophageal junction cancer | Phase 2 | TW | 06 Dec 2023 | |
HER2 negative Gastric Cancer | Phase 2 | JP | 06 Dec 2023 | |
HER2 negative Gastric Cancer | Phase 2 | KR | 06 Dec 2023 | |
HER2 negative Gastric Cancer | Phase 2 | TW | 06 Dec 2023 | |
Advanced cancer | Phase 2 | US | 11 Sep 2018 | |
Advanced cancer | Phase 2 | BE | 11 Sep 2018 | |
Advanced cancer | Phase 2 | CA | 11 Sep 2018 | |
Stomach Cancer | Phase 2 | JP | - |
Phase 1 | Metastatic Colorectal Carcinoma Proficient DNA Mismatch Repair (pMMR) | Microsatellite Stable (MSS) | 34 | goprgmflvj(vpbxrthcou) = 28 (82.4%) with grade ≥3 and 20 (58.8%) with serious TEAEs; 15 patients (44.1%) discontinued of any study treatment due to TEAEs. No patient died due to TEAEs rueuyompkv (smctwntgkv ) | Positive | 30 Jun 2024 | ||
Phase 1 | Metastatic Colorectal Carcinoma PD-L1 combined positive score (CPS) | M1/M2 macrophages | 34 | hxlttfskdx(jbvyaedaly) = No patient died due to TEAEs umrbblqbrj (rzhmimkigx ) | Positive | 20 Jun 2024 | ||
Phase 1 | 31 | ainhknxqjl(bnchuymnoi) = bersbacubr orxlznpmyx (xrynrsjqah ) | Positive | 09 Sep 2022 | |||
dsysscbgwj(pxszxljohf) = fpfkmqhpmn abqalymzym (yevlzupcci ) View more |