Last update 14 Nov 2024

Brilacidin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Brilacidin (USAN), Brilacidin tetrahydrochloride, Brilacidin-Ocular
+ [5]
Mechanism
SARS-CoV-2 antigen inhibitors, Cell membrane permeability enhancers
Active Indication-
Originator Organization
Active Organization-
Drug Highest PhasePendingPhase 2
First Approval Date-
Regulation-
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Structure

Molecular FormulaC40H50F6N14O6
InChIKeyQPDYBCZNGUJZDK-DNQXCXABSA-N
CAS Registry1224095-98-0

External Link

KEGGWikiATCDrug Bank
D10414Brilacidin-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
COVID-19Phase 2
US
22 Feb 2021
COVID-19Phase 2
RU
22 Feb 2021
Head and Neck NeoplasmsPhase 2
US
14 Aug 2014
MucositisPhase 2
US
14 Aug 2014
radiation oral mucositisPhase 2
US
14 Aug 2014
Bacterial InfectionsPhase 2
US
01 Feb 2014
Skin Diseases, InfectiousPhase 2
US
01 Feb 2014
Methicillin-Resistant Staphylococcus Epidermidis (MRSE) InfectionPhase 2
CA
01 Oct 2010
Methicillin-Resistant Staphylococcus Epidermidis (MRSE) InfectionPhase 2
RU
01 Oct 2010
Methicillin-Resistant Staphylococcus Epidermidis (MRSE) InfectionPhase 2
UA
01 Oct 2010
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
120
Placebo
(Pooled Placebo + SoC)
nxlqyshgkp(dxryhdvwlo) = tdoeidlnhe ytylbzgkih (oelxoymxoc, jqkqhpjsvj - nvajcnnovq)
-
16 Sep 2022
(Brilacidin 3-dose + SoC)
nxlqyshgkp(dxryhdvwlo) = ucowdswkhi ytylbzgkih (oelxoymxoc, iggdnfnawj - aqunnfgxxk)
Phase 2
61
Placebo
(Placebo Oral Rinse)
amliskrwni(bbbkytqpaq) = ugcsayeoca mmhubpdxht (yurpaypiip, rlanmwwukt - sdrtmwaxev)
-
16 Jan 2019
(Active Oral Rinse)
amliskrwni(bbbkytqpaq) = mifqnrrcrn mmhubpdxht (yurpaypiip, rjngyjvhvz - ncjmeemxtw)
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Core Patent

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Clinical Trial

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Approval

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Regulation

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