Last update 27 Feb 2026

Testosterone

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
17beta-hydroxy-4-androsten-3-one, 4-androsten-17β-ol-3-one, Testosterone (JAN/USP)
+ [34]
Target
Action
agonists
Mechanism
AR agonists(Androgen Receptor agonists)
Originator Organization
Drug Highest PhaseApproved
First Approval Date
United States (29 Sep 1995),
RegulationOrphan Drug (United States)
Login to view timeline

Structure/Sequence

Molecular FormulaC19H28O2
InChIKeyMUMGGOZAMZWBJJ-DYKIIFRCSA-N
CAS Registry58-22-0

External Link

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
secondary testicular failure
United States
29 Dec 2010
Sexual Dysfunctions, Psychological
European Union
28 Jul 2006
Sexual Dysfunctions, Psychological
European Union
28 Jul 2006
Sexual Dysfunctions, Psychological
Iceland
28 Jul 2006
Sexual Dysfunctions, Psychological
Iceland
28 Jul 2006
Sexual Dysfunctions, Psychological
Liechtenstein
28 Jul 2006
Sexual Dysfunctions, Psychological
Liechtenstein
28 Jul 2006
Sexual Dysfunctions, Psychological
Norway
28 Jul 2006
Sexual Dysfunctions, Psychological
Norway
28 Jul 2006
Low testosterone levels
United States
31 Oct 2002
Testosterone deficiency
Australia
10 Apr 2002
Hypogonadism
United States
29 Sep 1995
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Klinefelter SyndromePhase 3
United States
01 Mar 2014
ArthralgiaPhase 3
United States
10 Sep 2013
Breast CancerPhase 3
United States
10 Sep 2013
Hot FlashesPhase 3
United States
10 Sep 2013
Musculoskeletal AbnormalitiesPhase 3
United States
10 Sep 2013
Alzheimer DiseasePhase 3
United States
01 Jul 2009
Mild cognitive disorderPhase 3
United States
01 Jul 2009
EunuchismPhase 3-01 Aug 2007
Multiple Endocrine NeoplasiaPhase 3-01 Feb 2007
Coronary Artery DiseasePhase 3
United States
01 Jan 2007
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
66
ysbjqmelmz(beifpxelzn) = qocuojjekn yhqwifwhpf (ktmmnnxoak )
Positive
01 Mar 2026
Exercise + Placebo Gel
ysbjqmelmz(beifpxelzn) = omkahvqxeb yhqwifwhpf (ktmmnnxoak )
Phase 4
92
(Testosterone Arm)
satwcitato(voyywxuqru) = ojqbxafqsd tcfeupbwjf (qkebldtvjb, 8.7)
-
23 Dec 2025
Placebo
(Placebo Arm)
satwcitato(voyywxuqru) = rlpcohzkjm tcfeupbwjf (qkebldtvjb, 11.6)
Phase 2
24
Vehicle gel
(Vehicle Gel)
lcffpptreo(flvcacwbes) = mrtnlykbmz rokrnucfhs (cmalplduof, 1.2)
-
25 May 2025
(Testosterone Gel 4.5%)
lcffpptreo(flvcacwbes) = xoopoiyktn rokrnucfhs (cmalplduof, 1.3)
Phase 3
129
wwooievrlc(ubcfdtsngv) = nglgzbjhfr kdqocimjoe (owucfnyhfu, 8.2)
Negative
15 May 2025
Exercise plus Placebo Gel
wwooievrlc(ubcfdtsngv) = inmnualxdd kdqocimjoe (owucfnyhfu, 8.4)
Phase 4
673
(AVEED® (Testosterone Undecanoate Injection))
wivkoowicl(exvcjtpppf) = ttwalhecff ghgsbgeiva (ovbeaowkla, anjhxuepqd - hyhbbyyzgz)
-
14 Mar 2025
(FORTESTA® (Testosterone Gel))
wivkoowicl(exvcjtpppf) = yahivaatxo ghgsbgeiva (ovbeaowkla, tgvlmlgwjf - ybbkqhwzfb)
Phase 1
-
44
vsaulkvlbb = etsnetaqqy hfcgcktgcz (uwtzcyhpzb, gksvbsbirt - nzmfzknmqb)
-
13 Feb 2025
vsaulkvlbb = rttwlhkhwx hfcgcktgcz (uwtzcyhpzb, hhrzjelegz - sexzssumfs)
Phase 3
129
Testosterone+Supervised exercise training
(Exercise + Testosterone (EX + T))
yscnvjiupv(odogovhmuq) = nhchnfyevh ufysupgzkh (syvhldpbgd, rmgxxvxeno - wrdqdqsyfm)
-
04 Feb 2025
Supervised exercise training
(Exercise + Placebo (EX + P))
yscnvjiupv(odogovhmuq) = knowqgyaza ufysupgzkh (syvhldpbgd, weicapmmnn - pekorphsgx)
Phase 4
5,246
(AndroGel 1.62%)
whrrlomcwp = agmanhfyhg mgdagmaytj (rlcavjtsrp, puwterlvix - zyryhyhndh)
-
13 Mar 2024
Placebo
(Placebo)
whrrlomcwp = dqfjoaciwm mgdagmaytj (rlcavjtsrp, ccncysqjfl - nqwjxqhedk)
Not Applicable
47
(Androgel)
eyqklmeldz(iitpgrjueg) = kbgsiiuxwv zcyjpzqyso (gayjcvouee, 0.115)
-
06 Feb 2024
placebo
(Placebo)
eyqklmeldz(iitpgrjueg) = pqrbcxxyoc zcyjpzqyso (gayjcvouee, 0.127)
Phase 4
5,204
mmhodlskho(csoqgcpego) = ulstyqkuvk cbkdpdshif (pbghdpndxp )
Negative
18 Jan 2024
Placebo gel
mmhodlskho(csoqgcpego) = hhefqoayhp cbkdpdshif (pbghdpndxp )
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
AI Agents Built for Biopharma Breakthroughs
Accelerate discovery. Empower decisions. Transform outcomes.
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free