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Last update 09 Oct 2025
C-019199
Last update 09 Oct 2025
Overview
Basic Info
Drug Type Small molecule drug |
Synonyms C 019199, C-019199, C019199 |
Target |
Action antagonists |
Mechanism CSF-1R antagonists(Colony stimulating factor 1 receptor antagonists), DDR1 antagonists(Discoidin domain receptor 1 antagonists), VEGFR2 antagonists(Vascular endothelial growth factor receptor 2 antagonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhasePhase 2 |
First Approval Date- |
Regulation- |
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Related
3
Clinical Trials associated with C-019199NCT06220318
A Phase I/II Clinical Study on the Safety, Tolerability and Preliminary Efficacy of C019199 in Combination With Sintilimab in Patients With Advanced Solid Tumors
CTR20223103
食物影响研究采用单中心、随机、开放、两周期、两序列、双交叉、单次空腹/餐后给药研究；剂量比例研究采用单中心、随机、开放、三周期、三序列、交叉、单次空腹给药研究。
[Translation] The food effect study was conducted using a single-center, randomized, open-label, two-period, two-sequence, double-crossover, single fasting/postprandial administration study; the dose proportionality study was conducted using a single-center, randomized, open-label, three-period, three-sequence, crossover, single fasting administration study.
CTR20202045
一项评价口服C019199片单次和多次给药在中国局部晚期或转移性实体瘤患者中的安全性、耐受性、药代动力学特征和抗肿瘤活性的多中心、开放、剂量递增的I期临床研究
[Translation] A multicenter, open-label, dose-escalation phase I clinical study to evaluate the safety, tolerability, pharmacokinetic characteristics and antitumor activity of single and multiple oral doses of C019199 tablets in Chinese patients with locally advanced or metastatic solid tumors
100 Clinical Results associated with C-019199
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100 Translational Medicine associated with C-019199
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100 Patents (Medical) associated with C-019199
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100 Deals associated with C-019199
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Locally Advanced Malignant Solid Neoplasm | Phase 2 | China | 19 Jul 2023 | |
| Osteosarcoma | Phase 2 | China | - | |
| Triple Negative Breast Cancer | Phase 2 | China | - | |
| Breast Cancer | Phase 1 | United States | 30 Jan 2022 | |
| Stomach Cancer | Phase 1 | United States | 30 Jan 2022 | |
| Stomach Cancer | Phase 1 | China | 30 Jan 2022 | |
| Colorectal Cancer | Phase 1 | China | 08 Mar 2021 | |
| Melanoma | Phase 1 | China | 08 Mar 2021 | |
| Pancreatic Cancer | Phase 1 | China | 08 Mar 2021 | |
| Soft Tissue Sarcoma | Phase 1 | China | 08 Mar 2021 |
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Clinical Result
Clinical Result
Indication
Phase
Evaluation
View All Results
Phase 1 | 30 | ggpzdglbkf(qkufqnczar) = lyqqocwimd fwacrtundq (eilctklkrx ) View more | Positive | 30 May 2025 | |||
Phase 1 | - | jdztafrljd(kgdxjlheil) = ymwllnqwnh lzsijdtewu (iqonsznfws ) View more | - | 02 Jun 2022 |
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