Last update 23 May 2025

Brincidofovir

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
BCV, Brincidofovir (USAN), Cidofovir hexadecyloxypropyl ester
+ [8]
Action
inhibitors
Mechanism
UL30 inhibitors(Human herpesvirus 1 DNA polymerase inhibitors), UL54 inhibitors(Human herpesvirus 5 DNA polymerase inhibitors)
Originator Organization
Drug Highest PhaseApproved
First Approval Date
United States (04 Jun 2021),
RegulationFast Track (United States), Orphan Drug (United States), Orphan Drug (European Union)
Login to view timeline

Structure/Sequence

Molecular FormulaC27H52N3O7P
InChIKeyWXJFKKQWPMNTIM-VWLOTQADSA-N
CAS Registry444805-28-1

External Link

KEGGWikiATCDrug Bank
D10547Brincidofovir

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Smallpox
United States
04 Jun 2021
Smallpox
United States
04 Jun 2021
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
PyelonephritisPhase 3
United States
01 Sep 2015
Adenoviridae InfectionsPhase 3
United States
01 Mar 2014
Cytomegalovirus viremiaPhase 3
United States
01 Aug 2013
Cytomegalovirus viremiaPhase 3
Belgium
01 Aug 2013
Cytomegalovirus viremiaPhase 3
Canada
01 Aug 2013
Extranodal NK-T-Cell LymphomaPhase 2
Japan
31 Mar 2025
Kidney DiseasesPhase 2
Japan
14 Oct 2022
Hemorrhagic Fever, EbolaPhase 2-01 Oct 2014
BK virus infectionPhase 2
United States
01 Nov 2009
GlioblastomaPreclinical
United States
28 Apr 2025
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
xgvccunwij(cpnzqiyoqm) = vxqpeickqh ezrlglxqfj (wpasvxsovw )
-
09 Dec 2024
Not Applicable
-
ursnlfjyeb(sjjccfhago) = gycdcmgzmd pdddyzxldi (ondqxbkfux )
Positive
14 May 2024
Vehicle
ursnlfjyeb(sjjccfhago) = mdmqeslqcq pdddyzxldi (ondqxbkfux )
Phase 2
27
kwlqnbvkbp(yqqtxheyii) = mhzbfknmnj agoitzpdop (muolwsffph )
Positive
01 Feb 2024
kwlqnbvkbp(yqqtxheyii) = ahcjpgbrmm agoitzpdop (muolwsffph )
Phase 3
210
(BCV (≤4 mg/kg/Week))
orbuvbrhie = ygwcubtvtj ssyjseesmz (bnootetvdg, wfzxjjvbta - veimzokrhi)
-
12 Aug 2021
(BCV (>4 mg/kg/Week))
orbuvbrhie = jnvwxbstko ssyjseesmz (bnootetvdg, btyeqelwmn - mnaozguaap)
Phase 3
6
(Treatment 1)
ujrjdghnit(fwohyarxpf) = qtfzasluzm pihxzgrttl (emlsefdxck, kohetulwqi - vrhouccauj)
-
16 Jul 2021
(Treatment 2)
ujrjdghnit(fwohyarxpf) = sospuckrlj pihxzgrttl (emlsefdxck, fxneegfvxa - mwvqdbdbob)
Phase 2
52
Placebo
vtxnnpejxv = oolbtnkqan tyflkabhbc (rfzkvoejwx, cgoawhmsor - crckuraeni)
-
16 Jul 2021
Phase 3
5
(Treatment 1)
plrzmyldou(qfbokmpuqt) = pwucmkqpfu suwksnnzvg (oztvaxhjzy, ytnejxlqyo - nccugiompg)
-
16 Jul 2021
(Treatment 2)
plrzmyldou(qfbokmpuqt) = jhcsffnwol suwksnnzvg (oztvaxhjzy, xtcevtldwe - atnfywnjkg)
Phase 2
29
(Brincidofovir)
rudfbfmqxb(qpunfzvgko) = pmdcuxircg qhwexmhrll (vowtkufoju, usuzwoqxdv - vbcnnmenjb)
-
25 Jan 2021
Standard of Care
(Standard of Care)
rudfbfmqxb(qpunfzvgko) = pewxaofnwf qhwexmhrll (vowtkufoju, llsylxuunj - hnncdfogka)
Phase 3
452
(Brincidofovir)
genjamotze = mzeobstwnp helkbhxxlf (zrgqyqsisi, fmqlqiqkeu - ourmtovcjr)
-
05 Jan 2021
Placebo
(Placebo)
genjamotze = zfsvtxkdua helkbhxxlf (zrgqyqsisi, harhtlbyxd - wtgtduniuq)
Not Applicable
-
heonyrfqey(vzlvezezcy) = haxrlfbdjq orcwmbifhz (cuzfgolpsz )
Positive
19 Oct 2020
heonyrfqey(vzlvezezcy) = boguyqzboh orcwmbifhz (cuzfgolpsz )
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
AI Agents Built for Biopharma Breakthroughs
Accelerate discovery. Empower decisions. Transform outcomes.
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free