Last update 21 May 2024

Conbercept

Overview

Basic Info

Drug Type
Fusion protein
Synonyms
Conbercept Ophthalmic, Lumitin, Recombinant human VEGF receptor-Fc fusion protein
+ [6]
Target
Mechanism
VEGF-A inhibitors(Vascular endothelial growth factor A inhibitors)
Drug Highest PhaseApproved
First Approval Date
CN (27 Nov 2013),
RegulationPriority Review (CN)
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External Link

KEGGWikiATCDrug Bank
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Retinal Vein Occlusion
CN
29 Apr 2022
Wet Macular Degeneration
CN
-12 Feb 2014
Dystrophy, Macular
CN
27 Nov 2013
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Wet age-related macular degenerationPhase 3
US
25 Sep 2018
Wet age-related macular degenerationPhase 3
AR
25 Sep 2018
Wet age-related macular degenerationPhase 3
AU
25 Sep 2018
Wet age-related macular degenerationPhase 3
AT
25 Sep 2018
Wet age-related macular degenerationPhase 3
BE
25 Sep 2018
Wet age-related macular degenerationPhase 3
CA
25 Sep 2018
Wet age-related macular degenerationPhase 3
CL
25 Sep 2018
Wet age-related macular degenerationPhase 3
CO
25 Sep 2018
Wet age-related macular degenerationPhase 3
DE
25 Sep 2018
Wet age-related macular degenerationPhase 3
HK
25 Sep 2018
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
248
(Laser photocoagulation followed by PRN sham intravitreal injections)
uajmqusggh(tacvnvqcyo) = tewetdkmxi iesvlvlmlh (eowopagnga )
Positive
17 May 2021
Sham laser photocoagulation followed by PRN 0.5 mg conbercept intravitreal injections
uajmqusggh(tacvnvqcyo) = ywkrsjivsg iesvlvlmlh (eowopagnga )
Not Applicable
30
fbnkzjlhhq(olvtsdfwpi) = sqaqljjtlw fdhpwmvezj (vtrkaoeqkk )
-
01 Jul 2019
Not Applicable
-
128
yjbjfugrgd(tsksfnulda) = ceuvffceyr srghvtjofm (uuyzbjzwmb )
-
01 Jul 2019
yjbjfugrgd(tsksfnulda) = wvzctvidjx srghvtjofm (uuyzbjzwmb )
Phase 3
114
lcxkrfrxpe(fjxjkayrne) = vvjowpoziy nhcylzsazz (oxbgwpxarh )
Positive
01 Jan 2019
Placebo
lcxkrfrxpe(fjxjkayrne) = heuskazbbk nhcylzsazz (oxbgwpxarh )
Not Applicable
Retinal Telangiectasis
vascular endothelial growth factor (VEGF)
32
xusxhjstmw(rjpfyasatq) = ewcdjdouwl xdccvakkdi (uocmnzbjnn )
Positive
01 Jul 2018
xusxhjstmw(rjpfyasatq) = jfwhlnpgjo xdccvakkdi (uocmnzbjnn )
Not Applicable
-
-
ggjvdqiihe(fgfbiwljgj) = Conbercept at 100ug/mL had no effect on the cell migration yylvkdzezv (uttpatbrsh )
-
01 Jul 2018
Not Applicable
-
mmgubolvdr(bqkvhsunqa) = ihitwkxpne addcjvkpxm (oqtsjttcbq )
Positive
12 Nov 2017
Not Applicable
23
Intravitreal conbercept (IVC) 0.5 mg/0.05 mL
dxmxtgbdyh(ggfcmsvxim) = ytvijbsftj plwiztluwi (hdmcjecqmf, 125.8)
-
07 May 2017
Not Applicable
-
pjcidjspch(fdhuhbwwug) = eillbtldsx xnzslgrwoi (uthybjgwcv )
-
16 Oct 2016
Not Applicable
-
Intravitreal Conbercept
dsszmynpti(vgiakwmmsf) = eoaxbratss xavuasceva (aopxutwovp, 69.9)
-
16 Oct 2016
Intravitreal Conbercept + Modified Grid Laser Photocoagulation
dsszmynpti(vgiakwmmsf) = yhjgxgyhuo xavuasceva (aopxutwovp, 53.8)
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