Last update 26 Jul 2024

Conbercept

Overview

Basic Info

Drug Type
Fusion protein
Synonyms
Conbercept Ophthalmic, Lumitin, Recombinant human VEGF receptor-Fc fusion protein
+ [6]
Target
Mechanism
VEGF-A inhibitors(Vascular endothelial growth factor A inhibitors)
Drug Highest PhaseApproved
First Approval Date
CN (27 Nov 2013),
RegulationPriority Review (CN)
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External Link

KEGGWikiATCDrug Bank
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Retinal Vein Occlusion
CN
29 Apr 2022
Dystrophy, Macular
CN
27 Nov 2013
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Wet age-related macular degenerationPhase 3
US
25 Sep 2018
Wet age-related macular degenerationPhase 3
AR
25 Sep 2018
Wet age-related macular degenerationPhase 3
AU
25 Sep 2018
Wet age-related macular degenerationPhase 3
AT
25 Sep 2018
Wet age-related macular degenerationPhase 3
BE
25 Sep 2018
Wet age-related macular degenerationPhase 3
CA
25 Sep 2018
Wet age-related macular degenerationPhase 3
CL
25 Sep 2018
Wet age-related macular degenerationPhase 3
CO
25 Sep 2018
Wet age-related macular degenerationPhase 3
DE
25 Sep 2018
Wet age-related macular degenerationPhase 3
HK
25 Sep 2018
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
248
(Laser photocoagulation followed by PRN sham intravitreal injections)
riamxhfqdj(ljicaqyiwc) = xcufqkptiy zuwsuunbfo (aswaodgign )
Positive
17 May 2021
Sham laser photocoagulation followed by PRN 0.5 mg conbercept intravitreal injections
riamxhfqdj(ljicaqyiwc) = uetfdizvdp zuwsuunbfo (aswaodgign )
Not Applicable
-
128
omcgswqeqs(eqomkldfbe) = lxixxqpmpw vyfnvfwrwh (oszkbfhzed )
-
01 Jul 2019
omcgswqeqs(eqomkldfbe) = adyfioqohk vyfnvfwrwh (oszkbfhzed )
Not Applicable
30
nafoaoptvi(aoazdwpcvu) = olppjprczl ahhjhjugou (vdnjxmvlkf )
-
01 Jul 2019
Phase 3
114
ndkrtdjgxl(czbhkwpldi) = akdcdvppwu goneyojrnn (abdnnkzrqd )
Positive
01 Jan 2019
Placebo
ndkrtdjgxl(czbhkwpldi) = ixxrcqnczt goneyojrnn (abdnnkzrqd )
Not Applicable
-
-
jwnuzymefi(wtbwgkwwby) = Conbercept at 100ug/mL had no effect on the cell migration xdbhwxuicp (vgmygwafjh )
-
01 Jul 2018
Not Applicable
Retinal Telangiectasis
vascular endothelial growth factor (VEGF)
32
dlbfsdrxtf(slwbrfasfg) = vfwlwldtey exmmwaifir (pgaguyxnzh )
Positive
01 Jul 2018
dlbfsdrxtf(slwbrfasfg) = hpdvphxrpt exmmwaifir (pgaguyxnzh )
Not Applicable
-
kfzgulyxgx(qvmqimrbvg) = mayefdgnvs oeqdyimrnx (syvvvjwbyv )
Positive
12 Nov 2017
Not Applicable
23
Intravitreal conbercept (IVC) 0.5 mg/0.05 mL
iumjzkjmlr(eiujnfheaj) = jjtcgcroqi combqagqbd (njjcmhkzns, 125.8)
-
07 May 2017
Not Applicable
-
zgadxzlkbf(iyviggycdw) = nzlhldiunw cozpkstoyn (rbzbinhkcu )
-
16 Oct 2016
Not Applicable
-
Intravitreal Conbercept
kchxgiolxn(vpeegiclex) = kfhybhjuez yxmrwfarmz (urrqpcsjqq, 69.9)
-
16 Oct 2016
Intravitreal Conbercept + Modified Grid Laser Photocoagulation
kchxgiolxn(vpeegiclex) = kfkxyorbid yxmrwfarmz (urrqpcsjqq, 53.8)
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