Drug Type Small molecule drug |
Synonyms MLN 8054, MLN8054 |
Target |
Mechanism Aurora A inhibitors(Serine/threonine-protein kinase Aurora-A inhibitors) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseDiscontinuedPhase 1 |
First Approval Date- |
Regulation- |
Molecular FormulaC25H15ClF2N4O2 |
InChIKeyHHFBDROWDBDFBR-UHFFFAOYSA-N |
CAS Registry869363-13-3 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Advanced cancer | Phase 1 | ES | 01 Apr 2006 | |
Advanced Malignant Solid Neoplasm | Phase 1 | US | 01 Oct 2005 | |
Bladder Cancer | Phase 1 | US | 01 Oct 2005 | |
Breast Cancer | Phase 1 | US | 01 Oct 2005 | |
Colonic Cancer | Phase 1 | US | 01 Oct 2005 | |
Pancreatic Cancer | Phase 1 | US | 01 Oct 2005 | |
Liver Cancer | Phase 1 | US | - | |
Solid tumor | Phase 1 | ES | - |
Phase 1 | 43 | eepyfdydag(wmfqawsglg) = facipljmub bclnykqnqe (gwpttubnmj ) | - | 20 May 2009 |