Last update 12 Jul 2025

ALX-0651

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
ALX 0651, ALX- 0651
Target
CXCR4
Action
modulators
Mechanism
CXCR4 modulators(C-X-C motif chemokine receptor 4 modulators)
Therapeutic Areas-
Active Indication-
Inactive Indication-
Originator Organization
Ablynx NVAblynx NV
Active Organization-
Inactive Organization
Ablynx NVAblynx NV
License Organization-
Drug Highest PhaseDiscontinuedPhase 1
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with ALX-0651
NL-OMON35929
/ CompletedNot Applicable
A phase I, single-centre, randomised, single-blinded, placebo-controlled single ascending dose study, followed by an open-label extension, evaluating the safety, pharmacokinetics, pharmacodynamics and efficacy of ALX 0651, administered intravenously to healthy male volunteers. - ALX 0651 SAD and open-label extension in healthy male
NCT01374503
/ TerminatedPhase 1
A Phase I, Single-centre, Randomised, Single-blinded, Placebo-controlled Single Ascending Dose Study, Followed by an Open-label Extension, Evaluating the Safety, Pharmacokinetics, Pharmacodynamics and Efficacy of ALX-0651, Administered Intravenously to Healthy Male Volunteers
100 Clinical Results associated with ALX-0651
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100 Translational Medicine associated with ALX-0651
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100 Patents (Medical) associated with ALX-0651
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100 Deals associated with ALX-0651
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R&D Status

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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Clinical Trial

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Approval

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Biosimilar

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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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