Last update 03 Mar 2026

RO-7268489

Overview

Basic Info

Drug Type
Unknown
Synonyms
RO-7268489
Target
MAGL
Action
inhibitors
Mechanism
MAGL inhibitors(Monoglyceride lipase inhibitors)
Therapeutic Areas
Immune System DiseasesNervous System DiseasesOther Diseases
Active Indication
Multiple Sclerosis, Chronic Progressive
Inactive Indication-
Originator Organization
Roche Holding AGRoche Holding AG
Active Organization
Roche Holding AGRoche Holding AG
Inactive Organization-
License Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with RO-7268489
NCT07282574
/ RecruitingPhase 2
A Multi-center, Double-blind, Placebo-controlled, Phase II Study Evaluating the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of RO7268489, a Monoacylglycerol Lipase Inhibitor, as Add-on Therapy to Ocrelizumab, in Participants With Progressive Forms of Multiple Sclerosis
100 Clinical Results associated with RO-7268489
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100 Translational Medicine associated with RO-7268489
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100 Patents (Medical) associated with RO-7268489
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100 Deals associated with RO-7268489
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Multiple Sclerosis, Chronic ProgressivePhase 2
New Zealand
Roche Holding AGRoche Holding AG
10 Mar 2026
Multiple Sclerosis, Chronic ProgressivePhase 2
Poland
Roche Holding AGRoche Holding AG
10 Mar 2026
Multiple Sclerosis, Chronic ProgressivePhase 2
Spain
Roche Holding AGRoche Holding AG
10 Mar 2026
Multiple Sclerosis, Chronic ProgressivePhase 2
Turkey
Roche Holding AGRoche Holding AG
10 Mar 2026
Multiple Sclerosis, Chronic ProgressivePhase 2
United Kingdom
Roche Holding AGRoche Holding AG
10 Mar 2026
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Clinical Trial

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Approval

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Regulation

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