Last update 21 Nov 2024
VC-005
Last update 21 Nov 2024
Overview
Basic Info
Drug Type Small molecule drug |
Synonyms |
Target |
Mechanism JAK1 inhibitors(Tyrosine-protein kinase JAK1 inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhasePhase 2 |
First Approval Date- |
Regulation- |
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Related
12
Clinical Trials associated with VC-005Safety, Tolerance and Pharmacokinetics Clinical Study of VC005 in Healthy Subjects and Patients With Mild to Moderate Atopic Dermatitis
评价VC005凝胶在健康受试者及轻中度特应性皮炎患者中的单次和多次给药的安全、耐受性和药代动力学研究
[Translation] To evaluate the safety, tolerability and pharmacokinetics of VC005 gel after single and multiple administration in healthy subjects and patients with mild to moderate atopic dermatitis
A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase II Clinical Study to Evaluate the Efficacy and Safety of VC005 Tablets in Adult Patients With Moderate to Severe Atopic Dermatitis
100 Clinical Results associated with VC-005
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100 Translational Medicine associated with VC-005
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100 Patents (Medical) associated with VC-005
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100 Deals associated with VC-005
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Moderate Atopic Dermatitis | Phase 2 | CN | - | 30 Jun 2023 |
| Severe Atopic Dermatitis | Phase 2 | CN | - | 30 Jun 2023 |
| Ankylosing Spondylitis | Phase 2 | CN | - | 21 Apr 2023 |
| Mild Atopic Dermatitis | Phase 1 | CN | - | 26 Jul 2023 |
| Rheumatoid Arthritis | Phase 1 | CN | - | 06 Jun 2023 |
| Inflammation | Phase 1 | CN | 30 Jan 2022 | |
| Inflammatory Bowel Diseases | Phase 1 | CN | - | 02 Nov 2021 |
| Eczema | IND Approval | CN | 17 Mar 2023 |
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Clinical Result
Clinical Result
Indication
Phase
Evaluation
View All Results
NCT05997927 (NEWS) Manual  | Phase 2 | - | (dwgefngqwx) = 治疗12周时，VC005高中低三个剂量组均达到主要终点，对比安慰剂组，显著改善EASI评分，疗效呈现良好的剂量相关性。 bconozblqv (qfxjxobitd ) Met View more | Positive | 20 Aug 2024 | ||
Placebo | |||||||
NCT05814939 (NEWS) Manual | Phase 2 | - | (yutiwpbszw) = VC005不同剂量组的患者病情显著改善，低剂量组在主要疗效终点上相对安慰剂有统计学意义的疗效差异，与阳性对照托法替布相当；高剂量组与托法替布组相比未出现指标恶化。 xeyihwvfcs (eerzbwyyiq ) View more | Positive | 05 Jul 2024 | ||
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