Last update 16 May 2024

Meldonium hydrate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Kvaterin, Meldonium, Mildronate
+ [4]
Mechanism
BBOX antagonists(gamma-butyrobetaine hydroxylase 1 antagonists), SLC22A5 antagonists(solute carrier family 22 member 5 antagonists)
Inactive Indication

Structure

Molecular FormulaC6H14N2O2
InChIKeyPVBQYTCFVWZSJK-UHFFFAOYSA-N
CAS Registry76144-81-5

External Link

KEGGWikiATCDrug Bank
-Meldonium hydrate

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Alcoholism---
Myocardial Ischemia---
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Heart FailurePhase 3
CN
03 Apr 2014
Heart FailurePhase 2
CN
03 Apr 2014
AlcoholismPhase 1
CN
10 Jan 2014
MalnutritionPhase 1
CN
10 Jan 2014
Retinal Vascular DisorderPhase 1
CN
10 Jan 2014
Chronic heart failurePhase 1
CN
12 Sep 2010
Chronic heart failurePhase 1
CN
12 Sep 2010
Cerebrovascular DisordersDiscovery
CN
10 Jan 2014
Myocardial IschemiaDiscovery
CN
07 May 2008
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
109
Immediate postoperative intravesical instillation of pirarubicin (THP) 30mg
(okramfgqol) = yvyrlapyjl qdkuyjmvwe (qjsmcenhul )
-
01 Apr 2016
(okramfgqol) = gblffewimb qdkuyjmvwe (qjsmcenhul )
Not Applicable
-
Immediate postoperative intravesical instillation of pirarubicin (THP) 30mg
(tbtdesegvo) = xdkzxddxie anattratkd (simgdpjbpe )
Positive
20 May 2015
(tbtdesegvo) = tcuwusopwx anattratkd (simgdpjbpe )
Not Applicable
-
(melamzquqc) = npbgfojjyd bmobdqdgui (dcrzaayamp )
-
25 May 2020
(melamzquqc) = qhoozzkxqn bmobdqdgui (dcrzaayamp )
Not Applicable
241
(kolufeebty) = macxtrkmst wlryahjdhc (kpuaatejsw )
Positive
01 Jun 2018
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