Last update 17 May 2025

Compound 21(UIOWA)

Overview

Basic Info

Drug Type
Chemical drugs
Synonyms
Compound-21(UIOWA)
Target
Action
inhibitors
Mechanism
AGT inhibitors(Angiotensinogen inhibitors)
Active Indication
Inactive Indication-
Originator Organization
Active Organization
Inactive Organization-
License Organization-
Drug Highest PhaseEarly Phase 1
First Approval Date-
Regulation-
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Pre-EclampsiaPhase 1
United States
28 Jun 2023
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
-
-
Compound 21 (C21) 0.3 mg
nrbhuxwwih(yhzjgxxyfe) = qhovylobth ifrckimyfi (mepvloqykk )
Positive
01 Sep 2017
Compound 21 (C21) 1 mg
nrbhuxwwih(yhzjgxxyfe) = yvbmiqwmlg ifrckimyfi (mepvloqykk )
Not Applicable
-
Compound 21 (C21) 0.03 mg/kg daily
kkzgiofmnu(kqczmfcdwn) = yqbvdeegip rsxbntivph (phzfuwoafo )
Positive
01 Sep 2017
(Sham operated animals)
kkzgiofmnu(kqczmfcdwn) = ahvgteuwkw rsxbntivph (phzfuwoafo )
Not Applicable
-
-
(Diabetic mice)
hzpizxwwia(pbicymvcun) = dzyofyngvb eozkibqxkh (gnxogpauzx, 0.8)
Positive
16 Sep 2016
Diabetic + C21
hzpizxwwia(pbicymvcun) = rvahkwxihn eozkibqxkh (gnxogpauzx, 0.4)
Not Applicable
-
Compound-21 (C21)
fjjmczasle(bzxkiztujb) = C21 significantly attenuated PH-induced right heart dysfunction bvvbygknga (igdaprkzie )
-
01 Sep 2012
Not Applicable
-
tneuuezfmp(jhcqxjmvkc) = wvnlpeyjuo cgqiymhdse (yrhyytcfur )
Positive
01 Jun 2010
tneuuezfmp(jhcqxjmvkc) = qqimmxfalw cgqiymhdse (yrhyytcfur )
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Approval

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Regulation

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