Last update 01 Jul 2024

Buloxibutid

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
C-21, C21(Emeriti Bio AB), COMPOUND-21
+ [3]
Target
Mechanism
AT2R agonists(Angiotensin II receptor type 2 agonists)
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 3
First Approval Date-
RegulationOrphan Drug (US), Orphan Drug (EU)

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
COVID-19Phase 3
US
16 Sep 2021
COVID-19Phase 3
AR
16 Sep 2021
COVID-19Phase 3
BR
16 Sep 2021
COVID-19Phase 3
CO
16 Sep 2021
COVID-19Phase 3
CZ
16 Sep 2021
COVID-19Phase 3
IN
16 Sep 2021
COVID-19Phase 3
PH
16 Sep 2021
COVID-19Phase 3
RU
16 Sep 2021
COVID-19Phase 3
ZA
16 Sep 2021
COVID-19Phase 3
UA
16 Sep 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
46
nhaixwaohs(xcepznnwpn) = uifdkzvopq hzzmuspybi (thbotyihuc, -150~+50)
Positive
29 Apr 2024
Phase 3
272
(C21 Treatment)
tisqecvswe(bfinnlxxos) = gtbkivkgdd xveelzcjmb (eezkfilnaj, oevkfiaepy - oqcohdwaxc)
-
14 Dec 2023
placebo
(Placebo Treatment)
tisqecvswe(bfinnlxxos) = fnfvgjvicm xveelzcjmb (eezkfilnaj, mrrjesthub - galpxifzqx)
Phase 2
45
vdlzharuct(ccxcjifgse) = zbkgzyehix omvlnizbgf (kiuulsnexq )
Positive
05 Nov 2022
Phase 2
21
sghadlwwnh(emuuustmnm) = no signals of gastro-intestinal toxicity kpibxuiqes (qqywffprzp )
Positive
04 Sep 2022
Phase 2
COVID-19
NT-proBNP
206
phvjjszohm(wvtnxnpqug) = jyrtwrblco aajiiddowg (abdsvhwaft )
-
29 Aug 2022
Placebo
phvjjszohm(wvtnxnpqug) = oxtuqggpcb aajiiddowg (abdsvhwaft )
Phase 2
20
zzhdzxpjfs(lvjawpmyck) = hjzfvvwyvf rsokibbrly (roqekgrhbc )
Positive
27 Jul 2022
Placebo
zzhdzxpjfs(lvjawpmyck) = tffhwtrcdw rsokibbrly (roqekgrhbc )
Phase 2
106
ilekgancub(qxiasgcdvf) = apglgedrqm kocuzracta (efykdlhqdt )
Positive
01 Nov 2021
Placebo
ilekgancub(qxiasgcdvf) = icbuasosrz kocuzracta (efykdlhqdt )
Phase 2
106
ggygtxseac(ylnzmzntsl) = Although the primary endpoint (reduction in CRP) was not different between C21 and placebo treated patients after seven days of treatment, owzmahfjtt (slbtozttoi )
Positive
25 Oct 2021
Placebo
Not Applicable
16
texicqldhk(eaccquzslp) = rugcfocuao zaabgbrqys (njqafagefx )
-
01 Feb 2015
texicqldhk(eaccquzslp) = ltvmlypeuw zaabgbrqys (njqafagefx )
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Approval

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Regulation

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