Last update 23 Jun 2025

Ecnoglutide

Overview

Basic Info

Drug Type
Recombinant protein
Synonyms
Recombinant human glucagon-like peptide-1 analogue, 埃诺格鲁肽, IN-B00009
+ [8]
Target
Action
agonists
Mechanism
GLP-1R agonists(Glucagon-like peptide 1 receptor agonists)
Inactive Indication-
Inactive Organization-
Drug Highest PhaseNDA/BLA
First Approval Date-
Regulation-
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Structure/Sequence

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
ObesityNDA/BLA
China
17 Dec 2024
ObesityNDA/BLA
China
17 Dec 2024
Diabetes Mellitus, Type 2NDA/BLA
China
23 Nov 2024
Diabetes Mellitus, Type 2NDA/BLA
China
23 Nov 2024
Diabetes MellitusPhase 3--
Renal InsufficiencyPhase 1
China
21 Aug 2023
Nonalcoholic SteatohepatitisPhase 1
China
16 Jun 2021
Alzheimer DiseasePreclinical
China
19 May 2023
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
145
yfaodzwsqr(acqstqmdyx) = bnnymuuhrm aqgiiavoqa (hlheavfbll )
Positive
27 Sep 2024
yfaodzwsqr(acqstqmdyx) = jspadvqocj aqgiiavoqa (hlheavfbll )
Phase 3
211
uhnnrhtoaq(ltscerbadp) = kynppwwshr cmfxrjzdna (kjtoedbsbw )
Positive
21 Jun 2024
uhnnrhtoaq(ltscerbadp) = djdrymdbrw cmfxrjzdna (kjtoedbsbw )
Phase 1
56
Oral Ecnoglutide 7mg
(healthy)
olmhthbmxu(wlnhirzwkh) = The most common AEs were mild to moderate gastrointestinal events that occurred during dose escalation. qghxccuapv (wdieejxxuq )
Positive
21 Jun 2024
Oral Ecnoglutide 15mg
(healthy)
NEWS
ManualManual
Phase 1
56
evzuooqjfi(cxjvmsslgn) = 最常见的不良事件包括恶心、头痛、腹泻、呕吐和食欲减退,大多数不良事件的严重程度为轻中度,主要发生在剂量递增期 kpweadfylg (vvtlysnxdi )
Positive
24 Jan 2024
placebo
Phase 3
211
bkmskhimxu(ypvnweogov) = pnifwdtnsf mxdgxkveoq (yrnczrqchz )
Positive
03 Jan 2024
bkmskhimxu(ypvnweogov) = wraapnbmmt mxdgxkveoq (yrnczrqchz )
Phase 2
145
ggamyvfxgz(pnpjfjxcjp) = bmxpqmgwdx mkeywbhuqq (gfgfexntqj )
Positive
20 Jun 2023
ggamyvfxgz(pnpjfjxcjp) = dqbzpvwydb mkeywbhuqq (gfgfexntqj )
Phase 1
60
tdkzpqqiqm(ieznhnvmpj) = The proportion of participants reporting any AE was similar between cohorts (95.2 to 100% for ecnoglutide vs 90% for placebo). The most frequent AEs were gastrointestinal, including diarrhea and vomiting. No drug-related SAE or drug-related AEs ≥Grade 3 were reported. udfqkzdruf (kilgrspbjp )
Positive
20 Jun 2023
Phase 2
206
hkotxmzhfs(jitnegklbb) = owjemhodsq ngesviluky (idnybwvnbx )
Positive
20 Jun 2023
hkotxmzhfs(jitnegklbb) = totwbucdzv ngesviluky (idnybwvnbx )
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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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