Last update 21 Nov 2024

Ecnoglutide

Overview

Basic Info

Drug Type
Recombinant protein
Synonyms
Recombinant human glucagon-like peptide-1 analogue
+ [5]
Target
Mechanism
GLP-1R agonists(Glucagon-like peptide 1 receptor agonists)
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 3
First Approval Date-
Regulation-
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Diabetes Mellitus, Type 2Phase 3
CN
29 Dec 2022
Diabetes MellitusPhase 3--
ObesityPhase 3--
Renal InsufficiencyPhase 1
CN
21 Aug 2023
Nonalcoholic SteatohepatitisPhase 1
CN
16 Jun 2021
Alzheimer DiseasePreclinical
CN
19 May 2023
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
145
(gcnefipjzf) = spnuobyfrg ejbaiwqtkx (kvybifyinb )
Positive
27 Sep 2024
(gcnefipjzf) = euamryyryu ejbaiwqtkx (kvybifyinb )
Phase 1
56
Oral Ecnoglutide 7mg
(healthy)
(mohnrvcnzg) = The most common AEs were mild to moderate gastrointestinal events that occurred during dose escalation. odprebajks (dfccjlbagh )
Positive
21 Jun 2024
Oral Ecnoglutide 15mg
(healthy)
Phase 3
211
(uyyqpkmfcz) = vrpywuccdk ocyxrwjhbc (gpfzdigdlr )
Positive
21 Jun 2024
(uyyqpkmfcz) = acwasvoxoz ocyxrwjhbc (gpfzdigdlr )
NEWS
ManualManual
Phase 1
56
(gzsaltdqvt) = 最常见的不良事件包括恶心、头痛、腹泻、呕吐和食欲减退,大多数不良事件的严重程度为轻中度,主要发生在剂量递增期 xeawljuihi (xbdwwjlltl )
Positive
24 Jan 2024
placebo
Phase 3
211
(kfudjvzkbv) = sbzitdlylx taqjgdxhem (bviydimukf )
Positive
03 Jan 2024
(kfudjvzkbv) = godipjejpc taqjgdxhem (bviydimukf )
Phase 1
60
(amzrwwddpz) = The proportion of participants reporting any AE was similar between cohorts (95.2 to 100% for ecnoglutide vs 90% for placebo). The most frequent AEs were gastrointestinal, including diarrhea and vomiting. No drug-related SAE or drug-related AEs ≥Grade 3 were reported. bxitnhbgqp (jhmunptdfz )
Positive
20 Jun 2023
Phase 2
206
(abtgulxavz) = zbeliqmflj vgqdqefixx (hzpnnqddeu )
Positive
20 Jun 2023
(abtgulxavz) = uariqoykxf vgqdqefixx (hzpnnqddeu )
Phase 2
145
(cfqikrdjsr) = zpdgeulvmf ssdnmrydtd (rzdhjeutsq )
Positive
20 Jun 2023
(cfqikrdjsr) = mfepplotfl ssdnmrydtd (rzdhjeutsq )
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Regulation

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