Last update 05 Nov 2024

Irbesartan/Amlodipine Besylate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Amlodipine besilate/irbesartan, Amlodipine/irbesartan, Aprovasc
+ [6]
Mechanism
AT1R antagonists(Angiotensin II Receptor Type 1 antagonists), VDCCs blockers(Voltage-gated calcium channel blockers)
Therapeutic Areas
Active Indication
Inactive Indication
Originator Organization
Drug Highest PhaseApproved
First Approval Date
JP (28 Sep 2012),
Regulation-
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Structure

Molecular FormulaC25H28N6O
InChIKeyYOSHYTLCDANDAN-UHFFFAOYSA-N
CAS Registry138402-11-6
View All Structures (2)

External Link

KEGGWikiATCDrug Bank
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Hypertension
JP
28 Sep 2012
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Essential HypertensionPhase 2
KR
21 May 2020
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
428
(IRB/AML 150/5 mg)
xkaebiywyg(ppmqqtqurn) = tufvctxzgt gxsiilpvcf (gmhjecqwkf, 12.35)
Positive
01 Jun 2024
(IRB/AML 150/10 mg)
xkaebiywyg(ppmqqtqurn) = wuwrnstwxv gxsiilpvcf (gmhjecqwkf, 12.78)
Not Applicable
-
Irbesartan/Amlodipine combination therapy
zzefudyscu(mkyyoomrhn) = significantly improved zgrtkfavax (fhsjvxdefw )
-
15 Nov 2016
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Regulation

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