Last update 08 May 2025

AXR-159

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Target
CD49d
Action
antagonists
Mechanism
CD49d antagonists(Integrin alpha-4 antagonists)
Therapeutic Areas
Eye Diseases
Active Indication-
Inactive Indication
Dry Eye Syndromes
Originator Organization
AxeroVision, Inc.
Active Organization-
Inactive Organization
AxeroVision, Inc.
License Organization-
Drug Highest PhasePendingPhase 2
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with AXR-159
NCT03598699
/ CompletedPhase 2
A Multicenter, Vehicle-controlled, Randomized Study to Evaluate the Safety, Tolerability, Systemic Pharmacokinetics, and Pharmacodynamics of AXR-159 Ophthalmic Solution 3 mg/mL, 30 mg/mL, and 50 mg/mL in Patients With Dry Eye Disease (DED)
100 Clinical Results associated with AXR-159
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100 Translational Medicine associated with AXR-159
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100 Patents (Medical) associated with AXR-159
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100 Deals associated with AXR-159
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Dry Eye SyndromesPhase 2
United States
AxeroVision, Inc.
26 Jun 2018
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
NCT03598699 (CTgov)
Phase 2
Dry Eye Syndromes
102
(AXR-159 Ophthalmic Solution 50 mg/mL)
ccoznobeeu(ozhpkexzhg) = gcyetmoecp uuajwkyaum (qpjzchoqgp, qkqgnekdni - sojrrstejc)
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-
13 Oct 2023
Vehicle
(AXR-159 Ophthalmic Solution Vehicle)
ccoznobeeu(ozhpkexzhg) = pnhclqtlnd uuajwkyaum (qpjzchoqgp, rnfecvhycp - imprblltka)
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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