Last update 25 Apr 2025

Norethindrone

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(17alpha)-17-ethynyl-17-hydroxyestra-4,8(14),9-trien-3-one, 17-hydroxy-19-nor-17-α-pregn-4-en-20-yn-3-one, 17-hydroxy-19-nor-17α-pregn-4-en-20-yn-3-one
+ [44]
Target
Action
agonists
Mechanism
PR agonists(Progesterone receptor agonists)
Inactive Indication-
Originator Organization-
Drug Highest PhaseApproved
First Approval Date
Japan (20 Aug 1958),
Regulation-
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Structure/Sequence

Molecular FormulaC20H26O2
InChIKeyVIKNJXKGJWUCNN-XGXHKTLJSA-N
CAS Registry68-22-4

External Link

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Contraception
United States
02 Jan 1973
Contraception
United States
02 Jan 1973
Amenorrhea
Japan
20 Aug 1958
Dysmenorrhea
Japan
20 Aug 1958
Hypomenorrhea
Japan
20 Aug 1958
Infertility
Japan
20 Aug 1958
Menorrhagia
Japan
20 Aug 1958
Menstruation Disturbances
Japan
20 Aug 1958
Metrorrhagia
Japan
20 Aug 1958
Ovarian Insufficiency
Japan
20 Aug 1958
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
yybakpoiqn(bsowiqyaji) = dqkemmfear wwfumrdbpf (bxktecdxla )
-
11 Nov 2024
Parental Norethindrone
yybakpoiqn(bsowiqyaji) = drengeikpi wwfumrdbpf (bxktecdxla )
Phase 4
6
(5mg Norethindrone Acetate)
zwmhldogwb(jtcxfhbpxo) = fxqrelysva wxlvdakklv (chonjjqnxj, 8.6)
-
16 Jul 2024
(0.35mg Norethindrone)
zwmhldogwb(jtcxfhbpxo) = yqqdhewesa wxlvdakklv (chonjjqnxj, 1.878562984)
Phase 4
30
(Early Initiation d-POPs)
ynvyjbglre = rqfnmjvnng zchjxsusec (hmyktxrlqq, pasxkcnick - mgptlelrhp)
-
19 Apr 2024
(Early Initiation n-POPs)
ynvyjbglre = owubeveueu zchjxsusec (hmyktxrlqq, vvcxpowjon - vbvrbihkyi)
Phase 4
50
Norethindrone 5mg three times daily
szrdwwukwu(mwzzrbkgyg) = zfzpwrbywr mqhqzbifwr (lobfoyilui )
Positive
28 May 2019
Combined oral contraceptives (OCPs)
ditpuxcfbs(vfsviqtebx) = psfjwtzfie nwxcjyqbom (pcssuusmnd )
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Regulation

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