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Last update 08 May 2025
ZG-006
Last update 08 May 2025
Overview
Basic Info
Drug Type Trispecific T-cell engager (TriTE) |
Synonyms |
Target- |
Action stimulants, inhibitors |
Mechanism CD3 stimulants(T cell surface glycoprotein CD3 stimulants), DLL3 inhibitors(Delta-like protein 3 inhibitors) |
Therapeutic Areas |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhasePhase 1/2 |
First Approval Date- |
RegulationOrphan Drug (United States) |
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Related
7
Clinical Trials associated with ZG-006NCT06592638
A Phase 1 Dose Escalation Study of the Tolerability, Safety, Efficacy and Pharmacokinetics of ZG006 in Patients With Small Cell Lung Cancer
NCT06283719
A Phase I Dose Escalation Study of Tolerability, Safety, Efficacy, and Pharmacokinetics of ZG006 in Participants With Advanced Small Cell Lung Cancer or Neuroendocrine Carcinoma, Followed by a Phase II Dose Expansion Study in Participants With Advanced Small Cell Lung Cancer
NCT06440057
A Phase I Dose Escalation Study of Tolerability, Safety, Efficacy, and Pharmacokinetics of ZG006 in Participants With Advanced Small Cell Lung Cancer or Neuroendocrine Carcinoma, Followed by a Phase II Dose Expansion Study in Participants With Neuroendocrine Carcinoma.
100 Clinical Results associated with ZG-006
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100 Translational Medicine associated with ZG-006
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100 Patents (Medical) associated with ZG-006
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100 Deals associated with ZG-006
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Advanced Neuroendocrine Carcinoma | Phase 2 | China | 12 Aug 2024 | |
| Advanced Lung Small Cell Carcinoma | Phase 2 | China | 19 Oct 2023 | |
| Small Cell Lung Cancer | Phase 1 | United States | 31 Mar 2025 |
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Clinical Result
Clinical Result
Indication
Phase
Evaluation
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Phase 1/2 | 24 | (jnlrtxymch) = 绝大多数治疗相关不良事件（TRAEs）的严重程度为1级或2级。最常见的TRAEs为发热、贫血和细胞因子释放综合征（CRS，3级CRS 1例）。 slcpergcox (zavkajaohg ) View more | Positive | 25 Sep 2024 |
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