Last update 21 Nov 2024
ZG-006
Last update 21 Nov 2024
Overview
Basic Info
Drug Type Trispecific T-cell engager (TriTE) |
Synonyms |
Target |
Mechanism CD3 inhibitors(T cell surface glycoprotein CD3 inhibitors), DLL3 inhibitors(Delta-like protein 3 inhibitors) |
Therapeutic Areas |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhasePhase 1/2 |
First Approval Date- |
RegulationOrphan Drug (US) |
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Related
7
Clinical Trials associated with ZG-006A Phase 1 Dose Escalation Study of the Tolerability, Safety, Efficacy and Pharmacokinetics of ZG006 in Patients with Small Cell Lung Cancer
ZG006在晚期小细胞肺癌或神经内分泌癌患者中的耐受性、安全性、有效性和药代动力学的 I 期剂量递增及在晚期神经内分泌癌患者中的 II 期剂量扩展临床研究
[Translation] Phase I dose-escalation study of the tolerability, safety, efficacy and pharmacokinetics of ZG006 in patients with advanced small cell lung cancer or neuroendocrine carcinoma and Phase II dose-expansion study in patients with advanced neuroendocrine carcinoma
A Phase I Dose Escalation Study of Tolerability, Safety, Efficacy, and Pharmacokinetics of ZG006 in Participants With Advanced Small Cell Lung Cancer or Neuroendocrine Carcinoma, Followed by a Phase II Dose Expansion Study in Participants With Neuroendocrine Carcinoma.
100 Clinical Results associated with ZG-006
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100 Translational Medicine associated with ZG-006
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100 Patents (Medical) associated with ZG-006
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100 Deals associated with ZG-006
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Advanced Neuroendocrine Carcinoma | Phase 2 | CN | 12 Aug 2024 | |
| Advanced Lung Small Cell Carcinoma | Phase 2 | CN | 19 Oct 2023 | |
| Small Cell Lung Cancer | IND Application | US | 10 Apr 2023 |
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Clinical Result
Clinical Result
Indication
Phase
Evaluation
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Phase 1/2 | 24 | (tcyngvtdiv) = 绝大多数治疗相关不良事件（TRAEs）的严重程度为1级或2级。最常见的TRAEs为发热、贫血和细胞因子释放综合征（CRS，3级CRS 1例）。 tvsxalvxdt (rszcheabfb ) View more | Positive | 25 Sep 2024 |
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