Last update 04 Nov 2024

Chiauranib

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Ibcasertib, CS-2164
Mechanism
Aurora B inhibitors(Serine/threonine-protein kinase Aurora-B inhibitors), CSF-1R antagonists(Colony stimulating factor 1 receptor antagonists), VEGFR antagonists(Vascular endothelial growth factor receptor antagonists)
Inactive Organization-
Drug Highest PhasePhase 3
First Approval Date-
RegulationOrphan Drug (US), Breakthrough Therapy (CN), Special Review Project (CN)
Login to view timeline

Structure

Molecular FormulaC27H21N3O3
InChIKeyBRKWREZNORONDU-UHFFFAOYSA-N
CAS Registry1256349-48-0

External Link

KEGGWikiATCDrug Bank
---

R&D Status

10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Recurrent Platinum-Resistant Ovarian CarcinomaPhase 3
CN
20 Dec 2021
Small cell lung cancer recurrentPhase 3
CN
05 Mar 2021
Pancreatic Ductal AdenocarcinomaPhase 2
CN
13 Aug 2024
Metastatic Pancreatic Ductal AdenocarcinomaPhase 2-01 Aug 2024
Advanced Malignant Solid NeoplasmPhase 2
US
26 Aug 2022
Soft Tissue SarcomaPhase 2
CN
15 Aug 2022
Advanced Triple-Negative Breast CarcinomaPhase 2
CN
05 Nov 2021
Recurrent Non-Hodgkin LymphomaPhase 2
CN
11 Jul 2019
Recurrent ovarian cancerPhase 2
CN
01 Jul 2019
Advanced Hepatocellular CarcinomaPhase 2
CN
28 Apr 2018
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
28
aknzkwptwu(mekfwoffla) = gnixvleiqp qeoepksplr (yensnpwgdm, 6.06 - 36.89)
Positive
10 Apr 2021
Phase 1
18
nyawnqxcfu(djeohvdtmq) = grade 3 hypertension occurred in two patients at 65 mg/day npnpnsqhxc (hzfrdlnjno )
Positive
14 Jan 2019
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free