Last update 31 May 2025

SIBP-A13

Overview

Basic Info

Drug Type
Antibody drug conjugate (ADC)
Synonyms
SIBP-A13
Target
HER3 x Top I
Action
antagonists, inhibitors
Mechanism
HER3 antagonists(Receptor tyrosine-protein kinase erbB-3 antagonists), TOP1 inhibitors(DNA topoisomerase I inhibitors)
Therapeutic Areas
Neoplasms
Active Indication
Locally Advanced Malignant Solid Neoplasm
Inactive Indication-
Originator Organization
Shanghai Institute of Biological Products Co., Ltd.Shanghai Institute of Biological Products Co., Ltd.
Active Organization
Shanghai Institute of Biological Products Co., Ltd.Shanghai Institute of Biological Products Co., Ltd.
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC26H24FN3O6
InChIKeyPLXLYXLUCNZSAA-QLXKLKPCSA-N
CAS Registry1599440-33-1
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Related

1
Clinical Trials associated with SIBP-A13
NCT06298058
/ RecruitingPhase 1
A Phase I Clinical Study on the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of SIBP-A13 Injection in the Treatment of Advanced Malignant Solid Tumor Patients.
100 Clinical Results associated with SIBP-A13
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100 Translational Medicine associated with SIBP-A13
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100 Patents (Medical) associated with SIBP-A13
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100 Deals associated with SIBP-A13
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Locally Advanced Malignant Solid NeoplasmPhase 1
China
Shanghai Institute of Biological Products Co., Ltd.Shanghai Institute of Biological Products Co., Ltd.
09 May 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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