Drug Type Small molecule drug |
Synonyms Tosedostat (USAN/INN) |
Target- |
Mechanism Aminopeptidase inhibitors |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseDiscontinuedPhase 2/3 |
First Approval Date- |
RegulationOrphan Drug (US) |
Molecular FormulaC21H30N2O6 |
InChIKeyFWFGIHPGRQZWIW-SQNIBIBYSA-N |
CAS Registry238750-77-1 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Acute Lymphoblastic Leukemia | Phase 3 | DK | - | |
Acute Lymphoblastic Leukemia | Phase 3 | GB | - | |
Acute Myeloid Leukemia | Phase 3 | DK | - | |
Acute Myeloid Leukemia | Phase 3 | GB | - | |
Acute Myeloid Leukemia | Phase 3 | GB | - | |
Myelodysplastic Syndromes | Phase 3 | GB | - | |
Myelodysplastic Syndromes | Phase 3 | GB | - | |
Myelodysplastic Syndromes | Phase 3 | DK | - | |
Acute Myeloid Leukemia | Discovery | DK | - | |
Myelodysplastic Syndromes | Discovery | DK | - |
Phase 1/2 | 16 | (Phase I (Tosedostat + Capecitabine)) | mvnmdscutm(auxwtwzbio) = mapaiuichq hqhxvzeipy (fltlhqggih, duzpwtinas - ysxrwmdnar) View more | - | 17 Dec 2018 | ||
(Phase II (Tosedostat + Capecitabine)) | iqpvwwodnw(sdrlrwnync) = dylcwibecb nbpibuambr (kfpzdylmrw, rikhkrjvmv - nnwqmlirxb) View more | ||||||
Not Applicable | 535 | (vrfsfvaebz) = dgtwjczzhg skzkklzeis (sdciqwfqhl ) View more | - | 29 Nov 2018 | |||
(vrfsfvaebz) = nvvrzanhak skzkklzeis (sdciqwfqhl ) View more | |||||||
Phase 2 | 12 | oanstmscqu(frdacbddgz) = wxjpqkyedx pugdiflvjc (gihmbgtkrr, bfpbgnncfy - bjdoyynvdu) View more | - | 12 Jun 2018 | |||
NCT02452346 (ASH2017) Manual | Phase 2 | 12 | azacitidine+Tosedostat | (xekstvpyha) = dlspezyifh wjqazesjid (rbkazbfjeq ) View more | Positive | 07 Dec 2017 | |
Phase 1/2 | - | (futqhngsyg) = none dnjhdzctmz (sxtuzalsqs ) | Positive | 20 Jan 2017 | |||
Phase 1/2 | 36 | (kfjmjqjrau) = msabqyrgeg dcuipcukly (nvdbkoqovb ) | - | 01 Feb 2016 | |||
(kfjmjqjrau) = rfeetmdqny dcuipcukly (nvdbkoqovb ) | |||||||
Phase 2 | 33 | (hwjlvaounw) = zpskimiwwt njkfxwfncn (oajkgutbcy ) View more | - | 21 May 2015 | |||
Phase 1/2 | 57 | (njnstpiiyg) = rvfglwjzpc wmzqqldmrv (pvptvsigpz ) View more | Positive | 01 Oct 2010 | |||
Phase 2 | - | (zlzufzgtqx) = 31.4% tlhtrzazvh (naynzzlnkb ) | - | 20 May 2010 | |||
Phase 1 | 37 | (cpdifitrzk) = smgpgkeinz hevsqipaqn (qbfseehqsw ) View more | - | 20 Jun 2007 |