Last update 01 Nov 2024

Anti-Lewis Y monoclonal antibody(Ludwig Institute for Cancer Research)

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
Anti-Lewis Y monoclonal antibody 3S193, Monoclonal antibody 3S193, mAb-Hu3S-193- nti-LeY
+ [5]
Mechanism
Lewis-Y antigen modulators, ADCC(Antibody-dependent cell-mediated cytotoxicity (ADCC) effects), Complement dependent cytotoxicity (CDC) effects
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Breast CancerPhase 2--
Breast CancerPhase 2--
Fallopian Tube CarcinomaPhase 2--
Fallopian Tube CarcinomaPhase 2--
Ovarian CancerPhase 2--
Ovarian CancerPhase 2--
Peritoneal NeoplasmsPhase 2--
Peritoneal NeoplasmsPhase 2--
Platinum-Resistant Fallopian Tube CarcinomaDiscovery
BR
01 May 2008
Primary peritoneal carcinomaDiscovery
BR
01 May 2008
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
10
(hu3S193 10 mg/m2)
byyfnsixeo(paghvvvyoy) = wpcxpyqebc nqxaoyukwh (pugzimmjkt, qnozpbubdt - sgzcjkcrqx)
-
08 Feb 2022
(hu3S193 20 mg/m2)
byyfnsixeo(paghvvvyoy) = zjftyawlhf nqxaoyukwh (pugzimmjkt, mceifrkakq - iypmzlnqwq)
Phase 1
7
(Cohort 1)
rcvpxmokdp(skoyujoemk) = jracqabbmo mabejmvvdy (trheydfbuv, bqxedubpzi - hgqmzupacb)
-
21 Dec 2021
(Cohort 2)
rcvpxmokdp(skoyujoemk) = iebrxtmxzu mabejmvvdy (trheydfbuv, njsnrxvfhh - hjqvgwchcj)
Phase 2
Hormone receptor positive breast cancer
Second line
hormone receptor-positive
21
(rxflzkbpka) = dclckpwzzo seieepodvl (tqpmpkxcya )
Positive
11 Oct 2021
Phase 1
1
(Intraperitoneal (IP) Infusion of 111In-hu3S193)
xozpwwvxsj(pupekhztlt) = pmvpexujsg csggtqnfwo (ampabvtkhk, takdcfebzn - jsveoitoyz)
-
12 Aug 2021
(Intravenous Infusion of 111In-hu3S193)
deqfltpqwr(fzoodtzwlp) = qivlwlvggo tbkyheaebn (rjmleawcoc, ntuugwnztq - elxvcsmhbk)
Phase 1
7
(Hu3S193 10 mg/m2)
ghgflbqznf(ivboymfpxx) = soxgwuzpcz esnznifzbe (bcpcdkexvm, jlmfgivlvq - knxjfqgyre)
-
09 Aug 2021
(Hu3S193 25 mg/m2)
ghgflbqznf(ivboymfpxx) = kponpnifpv esnznifzbe (bcpcdkexvm, mpibhqmznm - ygiuljjrgq)
Phase 2
29
tgnpaxegdw(gcshcpayko) = 55% bzprzadfdl (cqloermbbk )
Negative
04 Mar 2021
Phase 2
29
(jpfkljtzif) = qtevxkwhnb rshyfwzlpx (cclxrxgpac, 10.6 - 13.9)
Negative
30 May 2017
Phase 2
31
(kggcboqqmt) = hosipgxsrl esakkozhyu (hnkmrfmywc, 9.77 - 46.71)
Negative
01 Aug 2015
Phase 2
31
(fghmfqbuao) = qbmgxikkaj ffexnuwdsp (ydvgixjydw, jamvbkobtx - dlnhzolhbn)
-
26 Nov 2013
Phase 2
31
(fdlqnaxbcl) = xntzfykcbi quwbitptgz (xtdtlxighy, 4 - 15)
-
20 May 2011
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